Basic Information
ID: ALA4417038
Type: Binding
Description: Inhibition of recombinant human N-terminal His-tagged MetAP2 (2 to 478 residues) using Met-Ala-Ser as substrate and MnCl2 as co-facor preincubated for 15 mins followed by substrate addition and measured after 45 mins by AAO/horse radish peroxidase enzyme coupled assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4417038
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 449.84 | 2.29 | 2.29 |
| 433.39 | 1.77 | 1.77 |
| 472.90 | 2.49 | 2.49 |
| 455.90 | 1.63 | 1.63 |
| 402.81 | 2.14 | 2.14 |
| 386.36 | 1.63 | 1.63 |
| 386.36 | 1.63 | 1.63 |
| 501.95 | 1.82 | 1.82 |
| 445.88 | 2.17 | 2.17 |
| 402.81 | 2.14 | 2.14 |
| 415.40 | 1.63 | 1.63 |
| 401.83 | 2.74 | 2.74 |
| 385.37 | 2.23 | 2.23 |
| 431.85 | 2.15 | 2.15 |
| 431.85 | 2.15 | 2.15 |
| 431.85 | 2.15 | 2.15 |
| 415.40 | 1.63 | 1.63 |
| 431.85 | 2.15 | 2.15 |
| 449.84 | 2.29 | 2.29 |
| 433.39 | 1.77 | 1.77 |
| 415.85 | 3.05 | 3.05 |
| 415.40 | 1.63 | 1.63 |
| 433.39 | 1.77 | 1.77 |
| 437.26 | 2.79 | 2.79 |
| 449.84 | 2.29 | 2.29 |
| 420.80 | 2.28 | 2.28 |