Basic Information
ID: ALA4417109
Type: Binding
Description: Ratio of IC50 for Inhibition of human N-terminal TEV protease cleavage site-fused-His6-tagged FPPS expressed in Escherichia coli BL21 (DE3) using GPP and [14C] IPP as substrate preincubated for 10 mins followed by substrate addition measured after 10 mins by scintillation counter method to IC50 for Inhibition of human N-terminal TEV protease cleavage site-fused-His6-tagged FPPS expressed in Escherichia coli BL21 (DE3) assessed as release of PPi using GPP and IPP as substrate preincubated for 30 mins followed by substrate addition by continuous spectrophotometric assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4417109
Ratio IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 290.11 | -1.12 | -1.12 |
| 314.43 | 3.63 | 3.63 |
| 382.46 | 3.45 | 3.45 |