Basic Information
ID: ALA4417110
Type: Binding
Description: Inhibition of human N-terminal TEV protease cleavage site-fused-His6-tagged FPPS expressed in Escherichia coli BL21 (DE3) assessed as using GPP and IPP as substrate preincubated for 30 mins followed by substrate addition in presence of 0.01 % Triton X-100 by continuous spectrophotometric assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4417110
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 346.47 | 4.40 | 4.40 |
| 290.11 | -1.12 | -1.12 |
| 371.48 | 4.25 | 4.25 |
| 514.46 | 5.95 | 5.95 |
| 358.43 | 2.98 | 2.98 |
| 511.62 | 4.72 | 4.72 |
| 375.51 | 3.34 | 3.34 |
| 314.43 | 3.63 | 3.63 |
| 410.47 | 3.34 | 3.34 |
| 429.56 | 4.26 | 4.26 |
| 342.39 | 2.34 | 2.34 |
| 344.45 | 4.28 | 4.28 |
| 382.46 | 3.45 | 3.45 |
| 413.56 | 4.72 | 4.72 |