Basic Information
ID: ALA4417325
Type: Binding
Description: Inhibition of human recombinant 5-LOX expressed in insect cells assessed residual activity using arachidonic acid at 42 uM as substrate preincubated for 5 mins followed by substrate addition measured after 20 mins in dark by ferric ion oxidation-xylenol orange method relative to control
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4417325
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 236.30 | 2.73 | 2.73 |
| 456.71 | 7.23 | 7.23 |
| 456.71 | 7.09 | 7.09 |
| 472.71 | 6.20 | 6.20 |
| 470.69 | 6.41 | 6.41 |
| 472.71 | 6.06 | 6.06 |
| 456.71 | 7.09 | 7.09 |
| 470.69 | 6.27 | 6.27 |
| 498.75 | 7.66 | 7.66 |
| 512.73 | 6.84 | 6.84 |
| 456.71 | 7.23 | 7.23 |
| 442.73 | 7.00 | 7.00 |
| 442.73 | 7.14 | 7.14 |
| 488.71 | 5.03 | 5.03 |
| 472.71 | 6.21 | 6.21 |
| 426.73 | 8.17 | 8.17 |
| 426.73 | 8.02 | 8.02 |
| 424.71 | 8.38 | 8.38 |
| 502.69 | 5.27 | 5.27 |
| 424.71 | 8.23 | 8.23 |
| 488.71 | 5.18 | 5.18 |
| 442.73 | 7.14 | 7.14 |
| 456.71 | 7.23 | 7.23 |
| 488.71 | 5.18 | 5.18 |
| 498.75 | 7.80 | 7.80 |
| 486.69 | 6.30 | 6.30 |
| 470.69 | 6.41 | 6.41 |
| 440.71 | 7.35 | 7.35 |
| 456.71 | 6.32 | 6.32 |
| 442.73 | 7.14 | 7.14 |