Assay Report Card

Basic Information

ID: ALA4417327

Type: Binding

Description: Inhibition of human recombinant N-terminal His-tagged 15-LOX2 expressed in Escherichia coli assessed as residual activity at 42 uM using arachidonic acid as substrate preincubated for 5 mins followed by substrate addition measured after 20 mins in dark by ferric ion oxidation-xylenol orange assay relative to control

Organism: Homo sapiens

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
302.373.573.57
456.717.237.23
456.717.097.09
472.716.206.20
470.696.416.41
472.716.066.06
456.717.097.09
470.696.276.27
498.757.667.66
512.736.846.84
456.717.237.23
442.737.007.00
442.737.147.14
488.715.035.03
472.716.216.21
426.738.178.17
426.738.028.02
424.718.388.38
502.695.275.27
424.718.238.23
488.715.185.18
442.737.147.14
456.717.237.23
488.715.185.18
498.757.807.80
486.696.306.30
470.696.416.41
440.717.357.35
456.716.326.32
442.737.147.14