Basic Information
ID: ALA4417328
Type: Binding
Description: Inhibition of ovine recombinant COX1 assessed as decrease in formation of PGE2 using arachidonic acid as substrate preincubated for 10 mins followed by substrate addition measured after 45 mins by LC-MS analysis
Organism: Ovis aries
Activity Charts
Bioactivity
Activity Types for Assay ALA4417328
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 352.74 | 5.22 | 5.22 |
| 456.71 | 7.23 | 7.23 |
| 456.71 | 7.09 | 7.09 |
| 472.71 | 6.20 | 6.20 |
| 470.69 | 6.41 | 6.41 |
| 472.71 | 6.06 | 6.06 |
| 456.71 | 7.09 | 7.09 |
| 470.69 | 6.27 | 6.27 |
| 498.75 | 7.66 | 7.66 |
| 512.73 | 6.84 | 6.84 |
| 456.71 | 7.23 | 7.23 |
| 442.73 | 7.00 | 7.00 |
| 442.73 | 7.14 | 7.14 |
| 488.71 | 5.03 | 5.03 |
| 472.71 | 6.21 | 6.21 |
| 426.73 | 8.17 | 8.17 |
| 426.73 | 8.02 | 8.02 |
| 424.71 | 8.38 | 8.38 |
| 502.69 | 5.27 | 5.27 |
| 424.71 | 8.23 | 8.23 |
| 488.71 | 5.18 | 5.18 |
| 442.73 | 7.14 | 7.14 |
| 456.71 | 7.23 | 7.23 |
| 488.71 | 5.18 | 5.18 |
| 498.75 | 7.80 | 7.80 |
| 486.69 | 6.30 | 6.30 |
| 470.69 | 6.41 | 6.41 |
| 440.71 | 7.35 | 7.35 |
| 456.71 | 6.32 | 6.32 |
| 442.73 | 7.14 | 7.14 |