Basic Information
ID: ALA4417330
Type: Binding
Description: Inhibition of human recombinant COX2 expressed in baculovirus infected sf21 cells assessed as decrease in PGE2 formation using arachidonic acid as substrate preincubated for 10 mins followed by substrate addition measured after 45 mins by LC-MS analysis
Organism: Homo sapiens
Cell type: Sf21
Activity Charts
Bioactivity
Activity Types for Assay ALA4417330
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 367.35 | 3.21 | 3.21 |
| 456.71 | 7.23 | 7.23 |
| 456.71 | 7.09 | 7.09 |
| 472.71 | 6.20 | 6.20 |
| 470.69 | 6.41 | 6.41 |
| 472.71 | 6.06 | 6.06 |
| 456.71 | 7.09 | 7.09 |
| 470.69 | 6.27 | 6.27 |
| 498.75 | 7.66 | 7.66 |
| 512.73 | 6.84 | 6.84 |
| 456.71 | 7.23 | 7.23 |
| 442.73 | 7.00 | 7.00 |
| 442.73 | 7.14 | 7.14 |
| 488.71 | 5.03 | 5.03 |
| 472.71 | 6.21 | 6.21 |
| 426.73 | 8.17 | 8.17 |
| 426.73 | 8.02 | 8.02 |
| 424.71 | 8.38 | 8.38 |
| 502.69 | 5.27 | 5.27 |
| 424.71 | 8.23 | 8.23 |
| 488.71 | 5.18 | 5.18 |
| 442.73 | 7.14 | 7.14 |
| 456.71 | 7.23 | 7.23 |
| 488.71 | 5.18 | 5.18 |
| 498.75 | 7.80 | 7.80 |
| 486.69 | 6.30 | 6.30 |
| 470.69 | 6.41 | 6.41 |
| 440.71 | 7.35 | 7.35 |
| 456.71 | 6.32 | 6.32 |
| 442.73 | 7.14 | 7.14 |