Basic Information
ID: ALA4417331
Type: Binding
Description: Inhibition of human recombinant COX2 expressed in baculovirus infected sf21 cells assessed as residual activity at 42 uM using arachidonic acid as substrate preincubated for 10 mins followed by substrate addition measured after 45 mins by LC-MS analysis relative to control
Organism: Homo sapiens
Cell type: Sf21
Activity Charts
Bioactivity
Activity Types for Assay ALA4417331
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 367.35 | 3.21 | 3.21 |
| 456.71 | 7.23 | 7.23 |
| 456.71 | 7.09 | 7.09 |
| 472.71 | 6.20 | 6.20 |
| 470.69 | 6.41 | 6.41 |
| 472.71 | 6.06 | 6.06 |
| 456.71 | 7.09 | 7.09 |
| 470.69 | 6.27 | 6.27 |
| 498.75 | 7.66 | 7.66 |
| 512.73 | 6.84 | 6.84 |
| 456.71 | 7.23 | 7.23 |
| 442.73 | 7.00 | 7.00 |
| 442.73 | 7.14 | 7.14 |
| 488.71 | 5.03 | 5.03 |
| 472.71 | 6.21 | 6.21 |
| 426.73 | 8.17 | 8.17 |
| 426.73 | 8.02 | 8.02 |
| 424.71 | 8.38 | 8.38 |
| 502.69 | 5.27 | 5.27 |
| 424.71 | 8.23 | 8.23 |
| 488.71 | 5.18 | 5.18 |
| 442.73 | 7.14 | 7.14 |
| 456.71 | 7.23 | 7.23 |
| 488.71 | 5.18 | 5.18 |
| 498.75 | 7.80 | 7.80 |
| 486.69 | 6.30 | 6.30 |
| 470.69 | 6.41 | 6.41 |
| 440.71 | 7.35 | 7.35 |
| 456.71 | 6.32 | 6.32 |
| 442.73 | 7.14 | 7.14 |