Basic Information
ID: ALA4417733
Type: Binding
Description: Inhibition of P-gp in human K562/R7 cells assessed as daunorubicin accumulation at 10 uM incubated fro 1 hr by flow cytometry relative to cyclosporine A
Format: BAO_0000219
Organism: Homo sapiens
Cell type: K562/R7
Target: P-glycoprotein 1(ALA4302)
Document: ALA4417622
Inhibition of P-gp in human K562/R7 cells assessed as daunorubicin accumulation at 10 uM incubated fro 1 hr by flow cytometry relative to cyclosporine A: 38
Activity Charts
Bioactivity
Activity Types for Assay ALA4417733
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 314.47 | 4.72 | 4.72 |
| 416.60 | 5.33 | 5.33 |
| 556.70 | 6.47 | 6.47 |
| 536.71 | 6.16 | 6.16 |
| 536.71 | 6.16 | 6.16 |
| 516.72 | 5.99 | 5.99 |
| 414.59 | 5.39 | 5.39 |
| 608.82 | 7.16 | 7.16 |
| 594.83 | 7.63 | 7.63 |
| 614.82 | 7.95 | 7.95 |
| 628.81 | 7.47 | 7.47 |
| 536.71 | 6.16 | 6.16 |
| 432.60 | 4.30 | 4.30 |
| 608.82 | 7.16 | 7.16 |
| 516.72 | 5.99 | 5.99 |
| 488.71 | 6.33 | 6.33 |
| 414.59 | 5.25 | 5.25 |
| 516.72 | 5.99 | 5.99 |
| 536.71 | 6.16 | 6.16 |
| 608.82 | 7.16 | 7.16 |
| 594.83 | 7.63 | 7.63 |
| 556.70 | 6.47 | 6.47 |