Basic Information
ID: ALA4417740
Type: Binding
Description: Inhibition of Rho/MRTF/SRF mediated signaling (unknown origin) assessed as reduction in MRTF/SRF-regulated gene transcription by SRE-luciferase expression based assay
Format: BAO_0000019
Organism: Homo sapiens
Target: Unchecked(ALA612545)
Document: ALA4417623
Inhibition of Rho/MRTF/SRF mediated signaling (unknown origin) assessed as reduction in MRTF/SRF-regulated gene transcription by SRE-luciferase expression based assay: 38
Activity Charts
Bioactivity
Activity Types for Assay ALA4417740
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 312.39 | 3.65 | 3.65 |
| 319.17 | 3.61 | 3.61 |
| 264.31 | 2.61 | 2.61 |
| 292.36 | 2.98 | 2.98 |
| 333.20 | 3.70 | 3.70 |
| 408.89 | 5.09 | 5.09 |
| 454.75 | 5.07 | 5.07 |
| 293.35 | 2.06 | 2.06 |
| 347.22 | 4.39 | 4.39 |
| 301.13 | 3.45 | 3.45 |
| 251.27 | 1.70 | 1.70 |
| 319.17 | 3.37 | 3.37 |
| 280.31 | 2.31 | 2.31 |
| 347.22 | 4.09 | 4.09 |
| 294.33 | 2.62 | 2.62 |
| 276.32 | 2.00 | 2.00 |
| 349.19 | 3.62 | 3.62 |
| 314.75 | 2.97 | 2.97 |
| 284.72 | 2.96 | 2.96 |
| 376.27 | 3.29 | 3.29 |
| 250.28 | 2.30 | 2.30 |
| 333.20 | 4.00 | 4.00 |
| 360.27 | 4.05 | 4.05 |
| 314.75 | 2.97 | 2.97 |
| 349.19 | 3.62 | 3.62 |
| 280.31 | 2.31 | 2.31 |
| 279.32 | 2.05 | 2.05 |
| 251.27 | 1.70 | 1.70 |
| 298.75 | 3.27 | 3.27 |
| 254.27 | 2.20 | 2.20 |
| 250.28 | 2.22 | 2.22 |
| 264.31 | 2.31 | 2.31 |
| 264.31 | 2.61 | 2.61 |
| 329.18 | 3.07 | 3.07 |
| 284.72 | 2.96 | 2.96 |
| 305.14 | 3.22 | 3.22 |
| 302.71 | 3.10 | 3.10 |
| 250.28 | 2.22 | 2.22 |
| 333.46 | 3.79 | 3.79 |
| 249.29 | 1.62 | 1.62 |