Assay Report Card

Basic Information

ID: ALA4417819

Type: Binding

Description: Stimulation of full-length recombinant human CYP46A1 assessed as cholesterol hydroxylation at 43 uM using cholesterol as substrate in presence of NADPH cytochrome P450 oxidoreductase by gas chromatography-mass spectrometry (Rvb = 100%)

Organism: Homo sapiens

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
151.161.351.35
179.262.032.03
151.161.351.35
179.222.042.04
137.181.671.67
193.252.432.43
151.161.351.35
149.191.951.95
165.191.651.65
195.221.021.02
165.191.141.14
207.272.822.82