Basic Information
ID: ALA4418098
Type: Binding
Description: Inhibition of helicase activity of flag-tagged recombinant DNA2 D277A mutant (unknown origin) expressed in 293T cells assessed as remaining 5' to 3' end-dependent DNA helicase activity at 100 mM using M13 phage DNA hybridized to 5'-tailed oligonucleotide substrate and [g-32P]ATP pre-incubated with 10 nM DNA2 enzyme for 1 min followed by substrate addition and measured after 30 mins by native polyacrylamide gel electrophoresis method relative to control
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4418098
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 234.17 | 1.55 | 1.55 |