Assay Report Card

Basic Information

ID: ALA4418114

Type: Binding

Description: Inhibition of DNA2 in 150 nM CPT-treated human A549 cells assessed as inhibition of DNA replication fork restart by measuring restarting forks levels at 20 uM pre-incubated for 40 mins followed by incubation with 250 uM C1dU for 40 mins by DNA fiber assay (Rvb = 75%)

Organism: Homo sapiens

Cell type: A549

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
234.171.551.55