Basic Information
ID: ALA4418132
Type: Binding
Description: Inhibition of human pendrin expressed in FRT cells co-expressing EYFP-HIF assessed as reduction in pendrin-mediated anion exchange at 25 uM incubated for 10 mins by pH-sensitive fluorescent probe BCECF-AM based fluorescence assay relative to control
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4418132
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 330.75 | 1.89 | 1.89 |
| 408.53 | 4.31 | 4.31 |
| 390.49 | 4.21 | 4.21 |
| 456.95 | 5.14 | 5.14 |
| 442.92 | 4.83 | 4.83 |
| 396.88 | 4.24 | 4.24 |
| 376.46 | 3.90 | 3.90 |
| 448.42 | 4.75 | 4.75 |
| 414.87 | 4.38 | 4.38 |
| 438.96 | 5.00 | 5.00 |
| 387.53 | 4.11 | 4.11 |
| 414.87 | 4.38 | 4.38 |
| 410.45 | 3.74 | 3.74 |
| 432.86 | 4.52 | 4.52 |
| 401.56 | 4.42 | 4.42 |
| 408.48 | 4.35 | 4.35 |
| 428.44 | 3.88 | 3.88 |
| 390.49 | 4.15 | 4.15 |
| 456.95 | 5.08 | 5.08 |
| 428.90 | 4.69 | 4.69 |
| 414.87 | 4.38 | 4.38 |
| 408.53 | 4.31 | 4.31 |