Basic Information
ID: ALA4418187
Type: Binding
Description: Inhibition of NAPRT in human CCRF-CEM cells assessed as potentiation of NAMPT inhibitor FK866-induced apoptosis by measuring reduction in cell viability at 3.5 mM prer-incubated with IC50 level of FK866 for 48 hrs followed by compound addition and further incubated for 48 hrs by Annexin-V/7-AAD staining based flow cytometry
Organism: Homo sapiens
Cell type: CCRF-CEM
Activity Charts
Bioactivity
Activity Types for Assay ALA4418187
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 180.16 | 1.31 | 1.31 |