Basic Information
ID: ALA4418216
Type: Binding
Description: Inhibition of DEPTOR in human RPMI8226 cells assessed as increase in mTOR kinase activity by measuring induction of p70 phosphorylation incubated for 6 hrs by Western blot analysis
Format: BAO_0000219
Organism: Homo sapiens
Target: DEP domain-containing mTOR-interacting protein(ALA4105866)
Document: ALA4417640
Inhibition of DEPTOR in human RPMI8226 cells assessed as increase in mTOR kinase activity by measuring induction of p70 phosphorylation incubated for 6 hrs by Western blot analysis: 38
Activity Charts
Bioactivity
Activity Types for Assay ALA4418216
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 231.90 | 2.69 | 2.69 |
| 440.11 | 5.72 | 5.72 |
| 308.00 | 4.85 | 4.85 |
| 325.99 | 4.99 | 4.99 |
| 376.88 | 6.15 | 6.15 |
| 336.00 | 4.16 | 4.16 |
| 259.95 | 3.30 | 3.30 |
| 288.01 | 4.12 | 4.12 |
| 314.04 | 4.66 | 4.66 |