Basic Information
ID: ALA4418325
Type: Binding
Description: Potency index, ratio of PRD-043 IC50 to test compound IC50 for inhibition ACAT2 in mouse hepatic microsome membranes using [1-14C]oleoyl coenzyme A as substrate incubated for 5 mins
Organism: Mus musculus
Activity Charts
Bioactivity
Activity Types for Assay ALA4418325
Ratio IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 675.73 | 5.06 | 5.06 |
| 791.85 | 5.69 | 5.69 |
| 698.77 | 5.56 | 5.56 |
| 732.79 | 6.21 | 6.21 |
| 645.71 | 5.05 | 5.05 |
| 642.66 | 4.44 | 4.44 |
| 656.69 | 4.53 | 4.53 |
| 726.82 | 6.19 | 6.19 |
| 782.93 | 8.04 | 8.04 |
| 794.86 | 7.51 | 7.51 |
| 698.77 | 5.56 | 5.56 |
| 732.79 | 6.21 | 6.21 |
| 688.78 | 6.85 | 6.85 |
| 681.76 | 7.12 | 7.12 |
| 688.78 | 6.85 | 6.85 |
| 681.76 | 7.12 | 7.12 |
| 688.78 | 6.85 | 6.85 |
| 681.76 | 7.12 | 7.12 |
| 704.78 | 6.55 | 6.55 |
| 692.74 | 6.68 | 6.68 |
| 702.80 | 7.16 | 7.16 |
| 702.80 | 7.16 | 7.16 |
| 724.81 | 7.69 | 7.69 |
| 639.74 | 5.03 | 5.03 |
| 717.82 | 6.61 | 6.61 |
| 655.79 | 6.94 | 6.94 |
| 587.67 | 5.37 | 5.37 |
| 697.76 | 6.82 | 6.82 |
| 695.81 | 7.18 | 7.18 |
| 707.86 | 6.59 | 6.59 |
| 685.72 | 6.95 | 6.95 |
| 649.74 | 6.67 | 6.67 |
| 695.78 | 7.42 | 7.42 |
| 746.81 | 6.23 | 6.23 |
| 583.63 | 3.76 | 3.76 |