Basic Information
ID: ALA4418328
Type: Binding
Description: Inhibition of GST-tagged human recombinant PASK expressed in Baculovirus based system using Ulight-peptide substrate incubated for 2 hrs by TR-FRET assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4418328
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 380.42 | 3.32 | 3.32 |
| 381.41 | 3.75 | 3.75 |
| 365.41 | 4.51 | 4.51 |
| 311.35 | 2.56 | 2.56 |
| 361.40 | 4.59 | 4.59 |
| 352.39 | 3.24 | 3.24 |
| 361.40 | 3.72 | 3.72 |
| 375.43 | 3.73 | 3.73 |
| 390.44 | 4.33 | 4.33 |
| 401.26 | 4.00 | 4.00 |
| 361.40 | 3.72 | 3.72 |
| 379.34 | 3.58 | 3.58 |
| 437.50 | 4.58 | 4.58 |
| 340.36 | 3.37 | 3.37 |
| 391.48 | 3.83 | 3.83 |
| 340.36 | 3.37 | 3.37 |
| 373.41 | 4.73 | 4.73 |
| 359.39 | 4.34 | 4.34 |
| 337.38 | 2.82 | 2.82 |
| 391.43 | 4.59 | 4.59 |
| 379.39 | 4.72 | 4.72 |
| 395.85 | 5.24 | 5.24 |
| 393.44 | 4.00 | 4.00 |
| 377.44 | 4.16 | 4.16 |
| 362.39 | 3.98 | 3.98 |
| 377.47 | 5.05 | 5.05 |
| 395.46 | 5.19 | 5.19 |
| 375.43 | 3.73 | 3.73 |
| 389.46 | 4.21 | 4.21 |
| 359.39 | 3.47 | 3.47 |
| 361.40 | 4.59 | 4.59 |
| 395.85 | 5.24 | 5.24 |
| 361.40 | 4.59 | 4.59 |
| 391.40 | 4.87 | 4.87 |
| 397.38 | 4.86 | 4.86 |
| 413.38 | 4.31 | 4.31 |
| 373.42 | 3.86 | 3.86 |
| 387.44 | 4.25 | 4.25 |
| 386.46 | 4.86 | 4.86 |
| 360.42 | 4.32 | 4.32 |
| 405.43 | 5.26 | 5.26 |
| 372.43 | 4.47 | 4.47 |
| 391.40 | 4.87 | 4.87 |
| 401.37 | 4.16 | 4.16 |
| 311.35 | 2.56 | 2.56 |
| 375.43 | 4.02 | 4.02 |
| 379.39 | 4.72 | 4.72 |
| 372.43 | 4.39 | 4.39 |
| 378.46 | 4.45 | 4.45 |
| 387.44 | 5.10 | 5.10 |
| 389.48 | 5.20 | 5.20 |
| 403.51 | 5.59 | 5.59 |
| 388.43 | 3.70 | 3.70 |
| 402.45 | 4.09 | 4.09 |
| 421.43 | 4.50 | 4.50 |
| 393.42 | 5.12 | 5.12 |
| 347.37 | 4.56 | 4.56 |
| 386.46 | 4.86 | 4.86 |
| 393.42 | 5.12 | 5.12 |
| 386.46 | 4.77 | 4.77 |
| 374.44 | 4.63 | 4.63 |
| 387.44 | 5.10 | 5.10 |
| 323.35 | 3.58 | 3.58 |
| 310.36 | 3.17 | 3.17 |
| 373.41 | 4.73 | 4.73 |
| 387.44 | 5.10 | 5.10 |
| 405.43 | 5.24 | 5.24 |
| 375.43 | 4.89 | 4.89 |
| 374.44 | 4.63 | 4.63 |
| 377.40 | 3.71 | 3.71 |
| 400.48 | 5.16 | 5.16 |
| 372.43 | 4.38 | 4.38 |
| 325.37 | 2.57 | 2.57 |
| 387.44 | 4.03 | 4.03 |
| 465.52 | 3.98 | 3.98 |
| 389.42 | 3.57 | 3.57 |
| 362.39 | 3.11 | 3.11 |
| 376.42 | 3.12 | 3.12 |
| 374.40 | 3.26 | 3.26 |
| 409.45 | 4.51 | 4.51 |
| 423.48 | 5.07 | 5.07 |
| 478.56 | 4.89 | 4.89 |
| 405.35 | 4.67 | 4.67 |
| 353.40 | 4.37 | 4.37 |
| 367.38 | 3.36 | 3.36 |
| 419.38 | 5.06 | 5.06 |
| 353.40 | 4.37 | 4.37 |
| 379.44 | 4.90 | 4.90 |
| 387.41 | 5.21 | 5.21 |
| 339.37 | 4.34 | 4.34 |
| 353.40 | 4.37 | 4.37 |
| 393.46 | 5.29 | 5.29 |
| 339.37 | 3.98 | 3.98 |
| 366.40 | 2.93 | 2.93 |
| 369.37 | 4.26 | 4.26 |
| 383.40 | 4.65 | 4.65 |
| 365.41 | 4.43 | 4.43 |
| 353.40 | 4.29 | 4.29 |
| 364.41 | 2.94 | 2.94 |
| 355.37 | 3.68 | 3.68 |
| 365.41 | 4.51 | 4.51 |
| 369.40 | 3.99 | 3.99 |
| 357.36 | 4.12 | 4.12 |
| 379.31 | 4.13 | 4.13 |
| 408.48 | 4.10 | 4.10 |
| 436.49 | 4.02 | 4.02 |
| 394.41 | 2.80 | 2.80 |
| 456.48 | 4.10 | 4.10 |
| 430.46 | 2.22 | 2.22 |
| 428.47 | 4.91 | 4.91 |
| 367.38 | 3.83 | 3.83 |
| 387.41 | 4.77 | 4.77 |
| 388.40 | 4.17 | 4.17 |
| 389.38 | 4.86 | 4.86 |
| 408.48 | 4.05 | 4.05 |
| 394.45 | 3.66 | 3.66 |
| 353.40 | 4.37 | 4.37 |
| 367.42 | 4.76 | 4.76 |
| 353.40 | 4.23 | 4.23 |
| 379.44 | 4.90 | 4.90 |
| 401.44 | 5.33 | 5.33 |
| 337.35 | 3.73 | 3.73 |
| 323.33 | 3.34 | 3.34 |
| 351.38 | 4.12 | 4.12 |
| 357.36 | 4.12 | 4.12 |
| 369.37 | 4.26 | 4.26 |
| 378.43 | 3.80 | 3.80 |
| 351.38 | 4.12 | 4.12 |
| 395.43 | 3.87 | 3.87 |
| 441.41 | 5.75 | 5.75 |
| 429.40 | 5.60 | 5.60 |
| 405.43 | 5.26 | 5.26 |