Basic Information
ID: ALA4418346
Type: Functional
Description: Antagonist activity at GPR6 (unknown origin) expressed in CHOK1 cells assessed as reduction in cAMP accumulation incubated for 45 mins and measured after 10 mins by Eu-cAMP tracer-based HTRF assay
Format: BAO_0000219
Organism: Homo sapiens
Target: G-protein coupled receptor 6(ALA3714130)
Document: ALA4418266
Antagonist activity at GPR6 (unknown origin) expressed in CHOK1 cells assessed as reduction in cAMP accumulation incubated for 45 mins and measured after 10 mins by Eu-cAMP tracer-based HTRF assay: 38
Activity Charts
Bioactivity
Activity Types for Assay ALA4418346
EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 444.49 | 3.20 | 3.20 |
| 389.43 | 4.37 | 4.37 |
| 414.87 | 3.88 | 3.88 |
| 517.60 | 4.01 | 4.01 |
| 419.48 | 3.32 | 3.32 |
| 389.43 | 4.37 | 4.37 |
| 443.46 | 2.02 | 2.02 |
| 474.56 | 3.57 | 3.57 |
| 387.85 | 3.76 | 3.76 |
| 458.51 | 3.33 | 3.33 |
| 444.49 | 3.20 | 3.20 |
| 460.94 | 3.71 | 3.71 |
| 460.94 | 3.71 | 3.71 |
| 476.57 | 3.26 | 3.26 |
| 421.47 | 3.86 | 3.86 |
| 421.47 | 3.86 | 3.86 |
| 449.48 | 3.42 | 3.42 |
| 387.41 | 4.13 | 4.13 |
| 417.46 | 3.64 | 3.64 |
| 373.41 | 3.49 | 3.49 |
| 419.48 | 3.32 | 3.32 |
| 373.41 | 3.49 | 3.49 |