Basic Information
ID: ALA4418348
Type: Functional
Description: Inhibition of TNF-alpha-induced CXCL10 production in HUVEC cells at 0.1 uM incubated for 1 hr followed by TNF-alpha addition and measured after 72 hrs by ELISA relative to control
Format: BAO_0000219
Organism: Homo sapiens
Cell type: HUVEC
Target: HUVEC(ALA613979)
Document: ALA4418268
Inhibition of TNF-alpha-induced CXCL10 production in HUVEC cells at 0.1 uM incubated for 1 hr followed by TNF-alpha addition and measured after 72 hrs by ELISA relative to control: 38
Activity Charts
Bioactivity
Activity Types for Assay ALA4418348
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 458.56 | 4.06 | 4.06 |
| 529.64 | 2.81 | 2.81 |
| 401.47 | 3.83 | 3.83 |
| 340.43 | 5.06 | 5.06 |
| 385.47 | 4.15 | 4.15 |
| 445.56 | 4.33 | 4.33 |
| 372.47 | 4.77 | 4.77 |
| 439.44 | 5.06 | 5.06 |
| 429.56 | 4.42 | 4.42 |
| 346.43 | 4.18 | 4.18 |
| 416.48 | 3.00 | 3.00 |
| 431.58 | 4.72 | 4.72 |
| 419.91 | 4.71 | 4.71 |
| 399.49 | 4.36 | 4.36 |
| 385.47 | 4.35 | 4.35 |
| 498.51 | 4.03 | 4.03 |
| 460.53 | 2.47 | 2.47 |
| 487.60 | 3.04 | 3.04 |
| 435.54 | 4.55 | 4.55 |
| 411.51 | 4.59 | 4.59 |
| 417.55 | 4.50 | 4.50 |
| 464.95 | 3.67 | 3.67 |
| 438.96 | 4.97 | 4.97 |
| 415.49 | 4.22 | 4.22 |
| 444.54 | 3.32 | 3.32 |
| 385.47 | 4.15 | 4.15 |
| 410.52 | 5.19 | 5.19 |
| 366.46 | 5.63 | 5.63 |
| 388.43 | 2.53 | 2.53 |
| 400.48 | 3.71 | 3.71 |
| 453.46 | 5.07 | 5.07 |
| 405.89 | 4.70 | 4.70 |
| 425.92 | 3.79 | 3.79 |
| 382.89 | 5.07 | 5.07 |
| 472.59 | 4.28 | 4.28 |
| 400.48 | 3.71 | 3.71 |
| 443.59 | 4.60 | 4.60 |
| 430.51 | 3.31 | 3.31 |
| 450.93 | 3.66 | 3.66 |
| 474.56 | 3.12 | 3.12 |
| 417.51 | 3.73 | 3.73 |
| 414.51 | 4.02 | 4.02 |
| 369.47 | 5.26 | 5.26 |
| 452.00 | 5.07 | 5.07 |
| 417.55 | 4.42 | 4.42 |
| 527.67 | 3.96 | 3.96 |
| 367.45 | 5.02 | 5.02 |
| 484.48 | 4.02 | 4.02 |
| 370.46 | 4.45 | 4.45 |
| 444.54 | 3.50 | 3.50 |
| 458.56 | 3.89 | 3.89 |