Assay Report Card

Basic Information

ID: ALA4418367

Type: Binding

Description: Inhibition of recombinant human SRR expressed in Escherichia coli assessed as reduction in conversion of L-serine to D-serine at 1 mM incubated for => 8 hrs in presence of PLP and recombinant D-serine dehydratase 1 by spectrophotometry relative to control

Organism: Homo sapiens

Activity Charts

Bioactivity

Activity Types for Assay ALA4418367

Inhibition

Total(62)

Compound Summary

Parent Molecular Weight	ALogP	Polar Surface Area
104.06	-0.45	-0.45
407.26	2.90	2.90
346.36	2.28	2.28
428.20	2.56	2.56
381.20	2.72	2.72
393.24	2.59	2.59
399.19	2.86	2.86
377.24	2.26	2.26
358.39	2.15	2.15
350.32	2.11	2.11
338.29	2.24	2.24
415.26	3.66	3.66
391.26	2.57	2.57
456.13	3.02	3.02
474.12	3.16	3.16
349.41	2.24	2.24
399.47	1.98	1.98
413.45	3.04	3.04
391.47	2.11	2.11
515.20	3.63	3.63
363.39	1.77	1.77
363.39	1.77	1.77
511.24	3.88	3.88
357.41	2.10	2.10
345.40	1.63	1.63
393.39	2.38	2.38
497.21	3.49	3.49
359.48	2.33	2.33
450.35	5.75	5.75
341.44	1.80	1.80
379.89	2.68	2.68
333.44	1.56	1.56
446.75	3.51	3.51
467.17	3.86	3.86
363.51	2.57	2.57
327.41	1.49	1.49
341.44	1.88	1.88
448.78	3.99	3.99
421.55	3.69	3.69
411.51	1.27	1.27
393.53	2.58	2.58
328.37	2.14	2.14
483.19	3.56	3.56
345.49	0.77	0.77
527.24	3.50	3.50
333.41	2.10	2.10
399.45	4.58	4.58
503.24	3.55	3.55
390.45	1.93	1.93
405.50	2.04	2.04
418.30	3.10	3.10
363.44	2.10	2.10
351.40	2.23	2.23
379.51	2.27	2.27
489.21	3.62	3.62
481.20	4.25	4.25
369.26	2.39	2.39
383.93	2.91	2.91
432.33	3.49	3.49
402.30	3.40	3.40
511.24	3.80	3.80
402.30	3.40	3.40