Basic Information
ID: ALA4418378
Type: Binding
Description: Inhibition of human LOXL2 expressed in CHO cells assessed as reduction in amine oxidase activity incubated for 2 hrs by Amplex red based fluorescence assay
Organism: Homo sapiens
Cell type: CHO
Activity Charts
Bioactivity
Activity Types for Assay ALA4418378
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 423.82 | 4.60 | 4.60 |
| 493.94 | 5.50 | 5.50 |
| 417.82 | 2.56 | 2.56 |
| 443.82 | 1.77 | 1.77 |
| 454.86 | 1.37 | 1.37 |
| 453.29 | 2.52 | 2.52 |
| 421.80 | 1.43 | 1.43 |
| 377.75 | 2.64 | 2.64 |
| 466.91 | 1.95 | 1.95 |
| 495.38 | 2.03 | 2.03 |
| 508.42 | 3.63 | 3.63 |
| 505.42 | 3.88 | 3.88 |
| 506.36 | 2.74 | 2.74 |
| 445.83 | 3.04 | 3.04 |
| 405.80 | 2.42 | 2.42 |
| 373.76 | 3.24 | 3.24 |
| 445.83 | 3.04 | 3.04 |
| 451.80 | 2.21 | 2.21 |
| 465.83 | 2.51 | 2.51 |
| 432.45 | 4.32 | 4.32 |
| 348.71 | 3.05 | 3.05 |
| 490.36 | 2.95 | 2.95 |
| 435.81 | 2.51 | 2.51 |
| 429.79 | 1.79 | 1.79 |
| 425.80 | 3.39 | 3.39 |
| 419.81 | 3.54 | 3.54 |
| 414.77 | 3.59 | 3.59 |
| 445.87 | 3.20 | 3.20 |
| 439.89 | 4.96 | 4.96 |
| 361.32 | 3.50 | 3.50 |
| 486.88 | 3.07 | 3.07 |
| 451.80 | 2.21 | 2.21 |
| 385.77 | 2.71 | 2.71 |
| 417.82 | 2.56 | 2.56 |
| 431.80 | 2.72 | 2.72 |
| 417.82 | 2.61 | 2.61 |
| 436.79 | 1.90 | 1.90 |
| 423.83 | 4.03 | 4.03 |
| 425.83 | 4.60 | 4.60 |
| 463.89 | 4.55 | 4.55 |
| 507.43 | 3.17 | 3.17 |
| 533.55 | 4.39 | 4.39 |
| 363.72 | 2.47 | 2.47 |
| 546.98 | 4.68 | 4.68 |
| 447.84 | 2.23 | 2.23 |
| 522.40 | 2.02 | 2.02 |
| 455.84 | 4.42 | 4.42 |
| 455.31 | 2.64 | 2.64 |
| 451.88 | 5.17 | 5.17 |
| 431.84 | 2.99 | 2.99 |
| 561.44 | 3.35 | 3.35 |
| 447.84 | 4.59 | 4.59 |
| 494.39 | 3.24 | 3.24 |
| 445.87 | 3.20 | 3.20 |
| 457.84 | 2.65 | 2.65 |
| 407.35 | 2.56 | 2.56 |
| 438.84 | 4.19 | 4.19 |
| 424.38 | 2.53 | 2.53 |
| 458.36 | 5.02 | 5.02 |
| 443.81 | 2.56 | 2.56 |
| 430.86 | 2.38 | 2.38 |
| 454.28 | 1.92 | 1.92 |
| 508.42 | 3.63 | 3.63 |
| 445.87 | 3.34 | 3.34 |
| 423.39 | 3.19 | 3.19 |
| 479.29 | 2.32 | 2.32 |
| 488.38 | 4.93 | 4.93 |
| 415.76 | 2.99 | 2.99 |
| 448.32 | 3.74 | 3.74 |
| 435.81 | 2.51 | 2.51 |
| 449.83 | 2.29 | 2.29 |
| 499.37 | 1.93 | 1.93 |
| 424.81 | 4.00 | 4.00 |
| 305.69 | 1.71 | 1.71 |
| 442.83 | 1.08 | 1.08 |
| 451.88 | 5.17 | 5.17 |
| 494.39 | 3.24 | 3.24 |
| 431.84 | 2.81 | 2.81 |
| 431.84 | 3.07 | 3.07 |
| 359.35 | 5.10 | 5.10 |
| 442.83 | 2.37 | 2.37 |
| 400.79 | 2.99 | 2.99 |
| 490.91 | 4.97 | 4.97 |
| 419.83 | 2.85 | 2.85 |
| 431.84 | 2.99 | 2.99 |
| 431.84 | 3.00 | 3.00 |
| 421.38 | 2.65 | 2.65 |
| 307.27 | 3.83 | 3.83 |
| 508.42 | 3.63 | 3.63 |
| 472.27 | 2.51 | 2.51 |
| 522.45 | 3.88 | 3.88 |
| 615.53 | 5.96 | 5.96 |
| 394.78 | 0.23 | 0.23 |
| 459.39 | 2.58 | 2.58 |
| 522.45 | 3.88 | 3.88 |
| 399.80 | 3.36 | 3.36 |
| 435.81 | 2.51 | 2.51 |
| 436.87 | 4.42 | 4.42 |
| 419.81 | 3.54 | 3.54 |
| 453.30 | 2.51 | 2.51 |
| 454.86 | 1.52 | 1.52 |
| 417.82 | 2.62 | 2.62 |
| 467.32 | 2.60 | 2.60 |
| 379.81 | 2.34 | 2.34 |
| 505.47 | 4.09 | 4.09 |
| 453.87 | 2.13 | 2.13 |
| 531.41 | 3.25 | 3.25 |
| 460.88 | 2.10 | 2.10 |
| 494.39 | 2.64 | 2.64 |
| 391.78 | 2.07 | 2.07 |
| 576.32 | 4.48 | 4.48 |
| 558.46 | 1.59 | 1.59 |
| 481.35 | 2.48 | 2.48 |
| 444.84 | 2.36 | 2.36 |
| 457.88 | 3.60 | 3.60 |
| 367.25 | 2.62 | 2.62 |
| 440.85 | 2.29 | 2.29 |
| 505.88 | 5.02 | 5.02 |
| 513.90 | 2.49 | 2.49 |
| 474.36 | 5.14 | 5.14 |