Basic Information
ID: ALA4418383
Type: Functional
Description: Antifibrotic activity in C57BL/6 mouse model of bleomycin-induced lung fibrosis assessed as reduction in hydroxyproline in lung homogenates at 60 mg/kg, po pre-treated 1 hr to 1 day before bleomycin injection and measured after 14 to 28 days by chloramine T and Erlich's solution based assay
Format: BAO_0000218
Organism: Mus musculus
Strain: C57BL/6
Tissue: Lung
Target: Mus musculus(ALA375)
Document: ALA4418283
Antifibrotic activity in C57BL/6 mouse model of bleomycin-induced lung fibrosis assessed as reduction in hydroxyproline in lung homogenates at 60 mg/kg, po pre-treated 1 hr to 1 day before bleomycin injection and measured after 14 to 28 days by chloramine T and Erlich's solution based assay: 38
Activity Charts
Bioactivity
Activity Types for Assay ALA4418383
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 423.82 | 4.60 | 4.60 |
| 443.82 | 1.77 | 1.77 |
| 373.76 | 3.24 | 3.24 |
| 435.81 | 2.51 | 2.51 |
| 472.27 | 2.51 | 2.51 |
| 453.87 | 2.13 | 2.13 |