Inhibition of untagged human USP30 catalytic domain (57 to 517 residues) expressed in Escherichia coli using TAMRA labeled ubiquitin peptide as substr...

Basic Information

ID: ALA4418408

Type: Binding

Description: Inhibition of untagged human USP30 catalytic domain (57 to 517 residues) expressed in Escherichia coli using TAMRA labeled ubiquitin peptide as substrate preincubated for 30 min followed by substrate addition and measured after 2 hrs by fluorescence polarization assay

Format: BAO_0000019

Organism: Homo sapiens

Target: Ubiquitin carboxyl-terminal hydrolase 30(ALA4523357)

Document: ALA4418285

Inhibition of untagged human USP30 catalytic domain (57 to 517 residues) expressed in Escherichia coli using TAMRA labeled ubiquitin peptide as substrate preincubated for 30 min followed by substrate addition and measured after 2 hrs by fluorescence polarization assay: 38

Associated Items: Associated Bioactivities Associated Compounds

Activity Charts

Bioactivity

Activity Types for Assay ALA4418408

IC50

Total(273)

Compound Summary

Parent Molecular Weight	ALogP	Polar Surface Area
356.43	0.43	0.43
283.29	1.02	1.02
291.35	2.64	2.64
325.37	1.38	1.38
407.47	1.88	1.88
283.29	1.02	1.02
307.36	1.70	1.70
340.81	3.03	3.03
284.32	1.35	1.35
326.79	2.69	2.69
308.34	1.97	1.97
363.40	2.66	2.66
312.40	2.34	2.34
282.31	0.76	0.76
335.37	1.25	1.25
327.36	1.85	1.85
332.82	2.75	2.75
334.38	1.85	1.85
333.40	1.89	1.89
331.33	1.65	1.65
326.34	1.64	1.64
310.33	2.17	2.17
300.36	1.36	1.36
312.40	2.34	2.34
313.34	1.51	1.51
292.34	2.03	2.03
367.31	2.52	2.52
342.40	0.07	0.07
321.38	2.65	2.65
292.34	2.03	2.03
348.82	1.72	1.72
311.35	1.37	1.37
281.32	1.16	1.16
293.33	1.43	1.43
298.37	2.10	2.10
372.43	0.65	0.65
336.40	2.35	2.35
283.29	1.02	1.02
317.39	2.98	2.98
283.29	1.02	1.02
270.34	1.35	1.35
342.40	3.19	3.19
316.75	2.28	2.28
292.34	2.03	2.03
292.34	2.03	2.03
284.36	1.74	1.74
297.32	0.16	0.16
325.80	3.29	3.29
318.35	0.95	0.95
298.35	0.71	0.71
292.34	2.03	2.03
305.38	2.57	2.57
307.36	1.50	1.50
376.46	2.15	2.15
311.35	1.37	1.37
312.40	2.34	2.34
334.38	1.67	1.67
342.30	2.86	2.86
335.41	2.00	2.00
301.35	0.20	0.20
327.36	1.99	1.99
346.41	1.72	1.72
310.36	2.24	2.24
295.35	1.37	1.37
357.39	1.62	1.62
305.38	2.98	2.98
346.41	1.58	1.58
307.35	2.76	2.76
313.34	1.51	1.51
313.34	1.60	1.60
282.30	1.63	1.63
326.79	2.69	2.69
299.31	1.50	1.50
313.34	1.51	1.51
348.35	0.98	0.98
335.41	2.00	2.00
314.39	1.59	1.59
382.85	3.04	3.04
338.37	1.98	1.98
351.41	1.72	1.72
293.33	1.43	1.43
327.36	1.90	1.90
325.80	3.29	3.29
327.36	1.82	1.82
312.40	2.34	2.34
337.38	1.71	1.71
391.48	2.41	2.41
412.44	1.97	1.97
391.48	2.41	2.41
336.37	2.52	2.52
327.36	1.82	1.82
300.36	0.81	0.81
347.42	1.93	1.93
339.37	1.85	1.85
349.40	1.59	1.59
356.81	2.70	2.70
347.42	1.93	1.93
362.44	2.10	2.10
312.33	1.64	1.64
347.42	1.93	1.93