Inhibition of human USP30 catalytic domain (57 to 517 residues) using ubiquitin-rhodamine 110 as substrate preincubated for 30 min followed by substra...

Basic Information

ID: ALA4418409

Type: Binding

Description: Inhibition of human USP30 catalytic domain (57 to 517 residues) using ubiquitin-rhodamine 110 as substrate preincubated for 30 min followed by substrate addition and measured after 2 hrs by fluorescence intensity kinetic assay

Format: BAO_0000357

Organism: Homo sapiens

Target: Ubiquitin carboxyl-terminal hydrolase 30(ALA4523357)

Document: ALA4418285

Inhibition of human USP30 catalytic domain (57 to 517 residues) using ubiquitin-rhodamine 110 as substrate preincubated for 30 min followed by substrate addition and measured after 2 hrs by fluorescence intensity kinetic assay: 38

Associated Items: Associated Bioactivities Associated Compounds

Activity Charts

Bioactivity

Activity Types for Assay ALA4418409

IC50

Total(273)

Compound Summary

Parent Molecular Weight	ALogP	Polar Surface Area
356.43	0.43	0.43
283.29	1.02	1.02
291.35	2.64	2.64
325.37	1.38	1.38
407.47	1.88	1.88
283.29	1.02	1.02
307.36	1.70	1.70
340.81	3.03	3.03
284.32	1.35	1.35
326.79	2.69	2.69
308.34	1.97	1.97
363.40	2.66	2.66
312.40	2.34	2.34
282.31	0.76	0.76
335.37	1.25	1.25
327.36	1.85	1.85
332.82	2.75	2.75
334.38	1.85	1.85
333.40	1.89	1.89
331.33	1.65	1.65
326.34	1.64	1.64
310.33	2.17	2.17
300.36	1.36	1.36
312.40	2.34	2.34
313.34	1.51	1.51
292.34	2.03	2.03
367.31	2.52	2.52
342.40	0.07	0.07
321.38	2.65	2.65
292.34	2.03	2.03
348.82	1.72	1.72
311.35	1.37	1.37
281.32	1.16	1.16
293.33	1.43	1.43
298.37	2.10	2.10
372.43	0.65	0.65
336.40	2.35	2.35
283.29	1.02	1.02
317.39	2.98	2.98
283.29	1.02	1.02
270.34	1.35	1.35
342.40	3.19	3.19
316.75	2.28	2.28
292.34	2.03	2.03
292.34	2.03	2.03
284.36	1.74	1.74
297.32	0.16	0.16
325.80	3.29	3.29
318.35	0.95	0.95
298.35	0.71	0.71
292.34	2.03	2.03
305.38	2.57	2.57
307.36	1.50	1.50
376.46	2.15	2.15
311.35	1.37	1.37
312.40	2.34	2.34
334.38	1.67	1.67
342.30	2.86	2.86
335.41	2.00	2.00
301.35	0.20	0.20
327.36	1.99	1.99
346.41	1.72	1.72
310.36	2.24	2.24
295.35	1.37	1.37
357.39	1.62	1.62
305.38	2.98	2.98
346.41	1.58	1.58
307.35	2.76	2.76
313.34	1.51	1.51
313.34	1.60	1.60
282.30	1.63	1.63
326.79	2.69	2.69
299.31	1.50	1.50
313.34	1.51	1.51
348.35	0.98	0.98
335.41	2.00	2.00
314.39	1.59	1.59
382.85	3.04	3.04
338.37	1.98	1.98
351.41	1.72	1.72
293.33	1.43	1.43
327.36	1.90	1.90
325.80	3.29	3.29
327.36	1.82	1.82
312.40	2.34	2.34
337.38	1.71	1.71
391.48	2.41	2.41
412.44	1.97	1.97
391.48	2.41	2.41
336.37	2.52	2.52
327.36	1.82	1.82
300.36	0.81	0.81
347.42	1.93	1.93
339.37	1.85	1.85
349.40	1.59	1.59
356.81	2.70	2.70
347.42	1.93	1.93
362.44	2.10	2.10
312.33	1.64	1.64
347.42	1.93	1.93