Basic Information
ID: ALA4418412
Type: Binding
Description: Inhibition of human LOXL2 expressed in CHO cells assessed as reduction in amine oxidase activity incubated for 2 hrs by Amplex red based fluorescence assay
Organism: Homo sapiens
Cell type: CHO
Activity Charts
Bioactivity
Activity Types for Assay ALA4418412
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 412.90 | 1.05 | 1.05 |
| 495.80 | 3.39 | 3.39 |
| 426.93 | 3.87 | 3.87 |
| 413.87 | 2.50 | 2.50 |
| 489.45 | 2.11 | 2.11 |
| 489.45 | 3.44 | 3.44 |
| 466.42 | 1.14 | 1.14 |
| 423.90 | 3.15 | 3.15 |
| 423.90 | 2.93 | 2.93 |
| 485.57 | 2.69 | 2.69 |
| 438.84 | 3.79 | 3.79 |
| 387.44 | 3.35 | 3.35 |
| 524.42 | 2.04 | 2.04 |
| 383.84 | 2.33 | 2.33 |
| 420.30 | 2.49 | 2.49 |
| 385.86 | 1.84 | 1.84 |
| 461.37 | 4.53 | 4.53 |
| 347.85 | 1.79 | 1.79 |
| 400.82 | 2.68 | 2.68 |
| 324.77 | 0.45 | 0.45 |
| 352.78 | 0.93 | 0.93 |
| 346.41 | 1.73 | 1.73 |
| 365.44 | 2.69 | 2.69 |
| 411.85 | 2.80 | 2.80 |
| 439.95 | 2.48 | 2.48 |
| 333.24 | 1.87 | 1.87 |
| 464.93 | 4.46 | 4.46 |
| 485.42 | 0.70 | 0.70 |
| 406.27 | 2.71 | 2.71 |
| 368.32 | 1.37 | 1.37 |
| 388.43 | 3.52 | 3.52 |
| 397.87 | 2.11 | 2.11 |
| 333.82 | 1.40 | 1.40 |
| 370.84 | 2.66 | 2.66 |
| 505.45 | 2.61 | 2.61 |
| 368.80 | 0.88 | 0.88 |
| 390.83 | 1.02 | 1.02 |
| 427.87 | 3.28 | 3.28 |
| 356.81 | 2.98 | 2.98 |
| 438.96 | 2.51 | 2.51 |
| 372.38 | 1.86 | 1.86 |
| 350.81 | 0.93 | 0.93 |
| 485.42 | 0.69 | 0.69 |
| 441.89 | 3.06 | 3.06 |
| 412.32 | 1.77 | 1.77 |
| 390.83 | 1.02 | 1.02 |
| 390.84 | -0.07 | -0.07 |
| 458.95 | 3.80 | 3.80 |
| 383.84 | 2.33 | 2.33 |
| 396.88 | 3.13 | 3.13 |
| 366.85 | 3.73 | 3.73 |
| 474.42 | 4.35 | 4.35 |
| 446.86 | 2.04 | 2.04 |
| 400.87 | 1.96 | 1.96 |
| 371.44 | 0.94 | 0.94 |
| 414.85 | 2.36 | 2.36 |
| 424.89 | 2.32 | 2.32 |
| 371.83 | 2.05 | 2.05 |
| 400.87 | 2.19 | 2.19 |
| 409.88 | 3.14 | 3.14 |
| 276.73 | 2.21 | 2.21 |
| 387.85 | -0.25 | -0.25 |
| 329.79 | 3.52 | 3.52 |
| 397.87 | 2.11 | 2.11 |
| 384.87 | 3.33 | 3.33 |
| 425.88 | 2.59 | 2.59 |
| 320.36 | 2.40 | 2.40 |
| 296.33 | 2.25 | 2.25 |
| 240.27 | 2.21 | 2.21 |
| 354.29 | 2.21 | 2.21 |
| 376.89 | 2.99 | 2.99 |
| 414.89 | 1.98 | 1.98 |
| 478.45 | 0.29 | 0.29 |
| 444.41 | 1.01 | 1.01 |
| 421.89 | 3.21 | 3.21 |
| 437.85 | 3.82 | 3.82 |
| 397.87 | 2.32 | 2.32 |
| 383.88 | 2.82 | 2.82 |
| 400.36 | 1.22 | 1.22 |
| 410.87 | 2.53 | 2.53 |
| 277.72 | 1.60 | 1.60 |
| 450.93 | 2.59 | 2.59 |
| 333.82 | 0.90 | 0.90 |
| 417.30 | 3.58 | 3.58 |
| 386.86 | 0.50 | 0.50 |
| 366.40 | 1.61 | 1.61 |
| 291.74 | 0.77 | 0.77 |
| 364.79 | 1.09 | 1.09 |
| 384.87 | 2.44 | 2.44 |
| 488.42 | 3.43 | 3.43 |
| 355.83 | 2.93 | 2.93 |
| 440.96 | 3.66 | 3.66 |
| 328.37 | 2.70 | 2.70 |
| 284.32 | 1.67 | 1.67 |
| 370.84 | 2.77 | 2.77 |
| 489.45 | 3.44 | 3.44 |
| 439.97 | 3.69 | 3.69 |
| 436.90 | 2.80 | 2.80 |
| 437.93 | 2.94 | 2.94 |
| 414.90 | 1.74 | 1.74 |
| 366.81 | 1.32 | 1.32 |
| 432.83 | 2.26 | 2.26 |
| 350.81 | 1.00 | 1.00 |
| 369.86 | 2.80 | 2.80 |
| 421.46 | 3.13 | 3.13 |
| 372.43 | 1.29 | 1.29 |
| 426.91 | 2.08 | 2.08 |