Basic Information
ID: ALA4418455
Type: Binding
Description: Inhibition of CGAS in human THP1 cells transfected with mock Sendai virus and measured after 16 hrs by Gaussia luciferase reporter gene assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4418455
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 489.71 | 3.56 | 3.56 |
| 418.19 | 4.78 | 4.78 |
| 437.28 | 2.77 | 2.77 |
| 378.25 | 4.28 | 4.28 |
| 441.31 | 4.85 | 4.85 |
| 364.22 | 3.89 | 3.89 |
| 528.39 | 4.20 | 4.20 |
| 452.29 | 2.48 | 2.48 |
| 488.32 | 3.38 | 3.38 |
| 451.30 | 3.33 | 3.33 |
| 484.35 | 2.93 | 2.93 |
| 451.30 | 3.23 | 3.23 |
| 457.31 | 3.83 | 3.83 |
| 566.41 | 5.39 | 5.39 |
| 475.30 | 3.97 | 3.97 |
| 517.36 | 2.65 | 2.65 |
| 299.74 | 2.72 | 2.72 |
| 330.16 | 2.53 | 2.53 |
| 456.71 | 3.84 | 3.84 |
| 382.21 | 4.03 | 4.03 |
| 528.39 | 4.20 | 4.20 |
| 477.34 | 3.76 | 3.76 |
| 440.25 | 3.33 | 3.33 |
| 471.34 | 4.14 | 4.14 |
| 513.35 | 3.39 | 3.39 |
| 410.25 | 3.12 | 3.12 |
| 457.31 | 3.83 | 3.83 |
| 467.28 | 3.38 | 3.38 |
| 439.26 | 3.93 | 3.93 |
| 471.33 | 4.95 | 4.95 |
| 446.29 | 1.72 | 1.72 |
| 469.29 | 3.47 | 3.47 |
| 515.39 | 4.21 | 4.21 |
| 426.33 | 4.78 | 4.78 |
| 487.73 | 4.70 | 4.70 |
| 442.29 | 4.25 | 4.25 |
| 548.42 | 5.26 | 5.26 |
| 360.25 | 2.99 | 2.99 |
| 421.27 | 3.79 | 3.79 |
| 471.34 | 4.29 | 4.29 |
| 455.27 | 2.91 | 2.91 |
| 474.70 | 3.98 | 3.98 |
| 451.30 | 3.08 | 3.08 |
| 505.40 | 2.96 | 2.96 |
| 362.18 | 2.97 | 2.97 |
| 344.19 | 2.83 | 2.83 |
| 451.30 | 2.81 | 2.81 |
| 489.33 | 4.43 | 4.43 |
| 391.19 | 2.67 | 2.67 |
| 358.21 | 3.22 | 3.22 |
| 368.21 | 2.83 | 2.83 |
| 437.28 | 2.77 | 2.77 |
| 546.38 | 4.34 | 4.34 |
| 484.35 | 3.32 | 3.32 |
| 507.32 | 4.67 | 4.67 |
| 536.30 | 4.64 | 4.64 |
| 497.41 | 4.09 | 4.09 |
| 416.22 | 4.98 | 4.98 |
| 421.27 | 3.79 | 3.79 |
| 422.26 | 3.59 | 3.59 |
| 497.37 | 4.71 | 4.71 |
| 353.20 | 1.78 | 1.78 |
| 448.28 | 3.77 | 3.77 |
| 535.41 | 3.90 | 3.90 |
| 479.35 | 4.14 | 4.14 |
| 469.29 | 3.22 | 3.22 |
| 459.32 | 4.88 | 4.88 |
| 478.30 | 2.42 | 2.42 |
| 474.31 | 4.70 | 4.70 |
| 566.41 | 5.39 | 5.39 |
| 398.16 | 3.72 | 3.72 |
| 499.32 | 2.83 | 2.83 |
| 483.32 | 3.86 | 3.86 |
| 410.25 | 3.12 | 3.12 |
| 528.39 | 4.20 | 4.20 |
| 363.23 | 4.49 | 4.49 |
| 501.36 | 3.65 | 3.65 |
| 456.32 | 4.56 | 4.56 |
| 471.34 | 4.39 | 4.39 |
| 515.39 | 4.31 | 4.31 |
| 436.29 | 3.38 | 3.38 |
| 461.30 | 3.67 | 3.67 |
| 468.30 | 3.37 | 3.37 |
| 504.39 | 3.99 | 3.99 |
| 499.32 | 2.73 | 2.73 |
| 462.30 | 3.70 | 3.70 |
| 477.34 | 3.65 | 3.65 |
| 439.29 | 2.77 | 2.77 |
| 506.38 | 2.60 | 2.60 |
| 437.28 | 2.77 | 2.77 |
| 476.74 | 4.90 | 4.90 |
| 469.29 | 3.47 | 3.47 |
| 469.29 | 2.95 | 2.95 |
| 455.27 | 2.91 | 2.91 |
| 522.38 | 4.12 | 4.12 |
| 358.21 | 3.22 | 3.22 |
| 489.33 | 4.53 | 4.53 |
| 483.28 | 2.59 | 2.59 |
| 422.26 | 3.19 | 3.19 |