Basic Information
ID: ALA4418460
Type: Binding
Description: Inhibition of untagged human USP30 catalytic domain (57 to 517 residues) expressed in Escherichia coli using TAMRA labeled ubiquitin peptide as substrate preincubated for 30 min followed by substrate addition and measured after 2 hrs by fluorescence polarization assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4418460
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 296.40 | 2.80 | 2.80 |
| 278.32 | 1.43 | 1.43 |
| 213.28 | 1.68 | 1.68 |
| 284.39 | 2.80 | 2.80 |
| 306.37 | 2.12 | 2.12 |
| 333.36 | 0.78 | 0.78 |
| 332.37 | 1.39 | 1.39 |
| 331.38 | 1.99 | 1.99 |
| 307.36 | 1.51 | 1.51 |
| 353.76 | 2.72 | 2.72 |
| 306.37 | 2.12 | 2.12 |
| 332.37 | 1.39 | 1.39 |
| 312.40 | 2.18 | 2.18 |
| 332.37 | 1.39 | 1.39 |
| 309.30 | 2.57 | 2.57 |
| 278.36 | 2.74 | 2.74 |
| 304.35 | 1.81 | 1.81 |
| 310.43 | 3.19 | 3.19 |
| 332.37 | 1.39 | 1.39 |
| 332.37 | 1.39 | 1.39 |
| 332.37 | 1.39 | 1.39 |
| 333.36 | 0.78 | 0.78 |
| 306.37 | 2.12 | 2.12 |
| 283.34 | 1.56 | 1.56 |
| 270.36 | 2.78 | 2.78 |
| 307.36 | 1.51 | 1.51 |
| 312.40 | 2.18 | 2.18 |