Basic Information
ID: ALA4418463
Type: Binding
Description: Inhibition of recombinant His-tagged human ATG7 at 0.123 uM incubated for 105 mins in presence of GST-tagged ATG3 and Flag-tagged Gabarap and measured after 2 hrs by FRET assay relative to control
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4418463
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 431.46 | -1.75 | -1.75 |
| 482.54 | -0.15 | -0.15 |
| 504.55 | 0.55 | 0.55 |
| 492.92 | -0.21 | -0.21 |
| 446.51 | -0.72 | -0.72 |
| 488.94 | 0.05 | 0.05 |
| 396.33 | -1.81 | -1.81 |
| 394.41 | -1.05 | -1.05 |
| 472.55 | -0.16 | -0.16 |
| 371.34 | -2.88 | -2.88 |
| 434.50 | -1.00 | -1.00 |
| 458.48 | -1.87 | -1.87 |
| 482.54 | 0.10 | 0.10 |
| 469.51 | -1.06 | -1.06 |
| 452.45 | -1.17 | -1.17 |
| 404.41 | -2.52 | -2.52 |
| 360.35 | -1.71 | -1.71 |
| 468.52 | -0.29 | -0.29 |
| 422.45 | -2.67 | -2.67 |
| 470.51 | 0.68 | 0.68 |
| 405.42 | -3.12 | -3.12 |
| 462.51 | -1.75 | -1.75 |
| 462.51 | -1.48 | -1.48 |
| 404.47 | -0.22 | -0.22 |
| 408.42 | -3.01 | -3.01 |
| 390.38 | -2.70 | -2.70 |
| 458.48 | -0.70 | -0.70 |
| 386.39 | -1.87 | -1.87 |
| 470.51 | 0.52 | 0.52 |
| 488.94 | 0.05 | 0.05 |
| 518.58 | 0.69 | 0.69 |
| 385.36 | -2.69 | -2.69 |
| 412.39 | -2.36 | -2.36 |
| 450.50 | -1.89 | -1.89 |
| 488.94 | 0.05 | 0.05 |
| 468.52 | -0.46 | -0.46 |
| 498.54 | -0.45 | -0.45 |
| 472.22 | -2.15 | -2.15 |
| 482.54 | -0.42 | -0.42 |
| 476.54 | -1.36 | -1.36 |
| 436.47 | -2.28 | -2.28 |
| 455.48 | -1.21 | -1.21 |
| 482.54 | -0.15 | -0.15 |
| 424.82 | -2.13 | -2.13 |
| 428.40 | -1.44 | -1.44 |
| 523.38 | 0.71 | 0.71 |
| 434.50 | -0.86 | -0.86 |
| 490.56 | -0.96 | -0.96 |
| 429.44 | -1.63 | -1.63 |
| 412.33 | -2.15 | -2.15 |
| 406.45 | -1.89 | -1.89 |
| 536.51 | 0.56 | 0.56 |
| 469.51 | -1.06 | -1.06 |
| 449.52 | -2.10 | -2.10 |
| 416.44 | -2.03 | -2.03 |
| 552.51 | 0.44 | 0.44 |
| 420.47 | -1.25 | -1.25 |
| 388.36 | -2.55 | -2.55 |
| 490.93 | 1.03 | 1.03 |
| 413.37 | -2.10 | -2.10 |
| 433.47 | -2.69 | -2.69 |
| 404.36 | -2.97 | -2.97 |
| 376.35 | -2.74 | -2.74 |
| 402.39 | -2.19 | -2.19 |
| 404.41 | -2.04 | -2.04 |
| 378.34 | -1.77 | -1.77 |
| 450.48 | -0.97 | -0.97 |
| 436.47 | -2.01 | -2.01 |
| 372.36 | -2.11 | -2.11 |
| 390.38 | -2.61 | -2.61 |
| 460.42 | -1.10 | -1.10 |
| 420.47 | -1.25 | -1.25 |
| 360.35 | -2.44 | -2.44 |
| 406.45 | -1.64 | -1.64 |
| 486.51 | -0.32 | -0.32 |
| 418.46 | -1.50 | -1.50 |