Basic Information
ID: ALA4418465
Type: Binding
Description: Inhibition of recombinant His-tagged human ATG7 at 0.111 uM incubated for 105 mins in presence of GST-tagged ATG3 and Flag-tagged Gabarap and measured after 2 hrs by FRET assay relative to control
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4418465
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 456.48 | 0.57 | 0.57 |
| 434.48 | -0.13 | -0.13 |
| 472.94 | 1.08 | 1.08 |
| 472.48 | -0.69 | -0.69 |
| 524.48 | 1.40 | 1.40 |
| 436.49 | 0.12 | 0.12 |
| 394.41 | -1.05 | -1.05 |
| 456.48 | 0.57 | 0.57 |
| 426.43 | -0.37 | -0.37 |
| 450.52 | 0.36 | 0.36 |
| 396.33 | -1.12 | -1.12 |
| 479.56 | -0.34 | -0.34 |
| 496.53 | 0.20 | 0.20 |
| 450.52 | 0.51 | 0.51 |
| 474.50 | -0.75 | -0.75 |
| 422.46 | -0.27 | -0.27 |
| 456.22 | -1.12 | -1.12 |
| 452.52 | 0.74 | 0.74 |
| 497.49 | -0.58 | -0.58 |
| 525.47 | 0.79 | 0.79 |
| 494.60 | 1.73 | 1.73 |
| 398.32 | -0.70 | -0.70 |
| 486.51 | 0.58 | 0.58 |
| 406.45 | -1.64 | -1.64 |
| 450.47 | -0.89 | -0.89 |
| 457.47 | -0.23 | -0.23 |
| 474.50 | -0.75 | -0.75 |
| 471.50 | 0.08 | 0.08 |
| 360.35 | -1.71 | -1.71 |
| 488.55 | 1.58 | 1.58 |
| 522.49 | 1.33 | 1.33 |
| 452.52 | 0.57 | 0.57 |
| 476.43 | 0.27 | 0.27 |
| 452.52 | 0.74 | 0.74 |
| 436.49 | 0.12 | 0.12 |
| 388.38 | -0.90 | -0.90 |
| 438.46 | -1.30 | -1.30 |
| 473.92 | 0.48 | 0.48 |
| 456.48 | 0.57 | 0.57 |
| 436.49 | 0.12 | 0.12 |
| 438.46 | -1.04 | -1.04 |
| 482.50 | 0.16 | 0.16 |
| 426.43 | -0.37 | -0.37 |
| 452.52 | 0.74 | 0.74 |
| 456.48 | 0.57 | 0.57 |
| 448.38 | -0.16 | -0.16 |
| 471.50 | 0.08 | 0.08 |
| 380.33 | -0.79 | -0.79 |
| 444.46 | -1.88 | -1.88 |
| 508.61 | 1.78 | 1.78 |
| 491.91 | 0.42 | 0.42 |
| 525.47 | 0.79 | 0.79 |
| 376.42 | -1.00 | -1.00 |
| 468.52 | 0.44 | 0.44 |
| 524.48 | 1.40 | 1.40 |
| 468.52 | -0.29 | -0.29 |
| 502.47 | -0.32 | -0.32 |
| 404.47 | -0.22 | -0.22 |
| 473.92 | 0.48 | 0.48 |
| 486.51 | -0.32 | -0.32 |
| 490.93 | 1.03 | 1.03 |
| 507.55 | -0.05 | -0.05 |
| 488.55 | 1.58 | 1.58 |
| 433.45 | -0.77 | -0.77 |
| 459.54 | 0.19 | 0.19 |
| 445.51 | -0.12 | -0.12 |
| 474.47 | 0.52 | 0.52 |
| 460.47 | -0.89 | -0.89 |
| 480.53 | 0.36 | 0.36 |
| 471.50 | 0.08 | 0.08 |
| 344.35 | -1.41 | -1.41 |
| 474.47 | 0.52 | 0.52 |
| 482.48 | -0.36 | -0.36 |
| 390.45 | -0.61 | -0.61 |
| 481.49 | 0.25 | 0.25 |
| 448.50 | 0.26 | 0.26 |
| 496.55 | 1.06 | 1.06 |
| 415.46 | -0.72 | -0.72 |
| 434.48 | -0.27 | -0.27 |
| 412.40 | -0.41 | -0.41 |
| 484.48 | 0.36 | 0.36 |
| 402.46 | -0.47 | -0.47 |
| 482.54 | -0.15 | -0.15 |
| 498.54 | 0.45 | 0.45 |
| 472.94 | 1.08 | 1.08 |
| 398.32 | -0.70 | -0.70 |
| 478.56 | 0.92 | 0.92 |
| 436.49 | 0.12 | 0.12 |
| 471.50 | -0.09 | -0.09 |
| 470.46 | -0.03 | -0.03 |
| 460.47 | -0.89 | -0.89 |
| 418.50 | 0.17 | 0.17 |
| 496.57 | 1.22 | 1.22 |
| 474.50 | 0.59 | 0.59 |
| 448.50 | 0.12 | 0.12 |
| 460.47 | -0.89 | -0.89 |
| 468.52 | -0.29 | -0.29 |
| 470.51 | 0.88 | 0.88 |
| 460.47 | 0.28 | 0.28 |
| 376.42 | -1.00 | -1.00 |
| 430.39 | -0.46 | -0.46 |
| 439.48 | -0.18 | -0.18 |
| 414.32 | -1.17 | -1.17 |
| 419.45 | -2.15 | -2.15 |
| 489.54 | 0.98 | 0.98 |
| 416.49 | -0.08 | -0.08 |
| 452.52 | 0.74 | 0.74 |
| 462.53 | 0.65 | 0.65 |
| 448.50 | -0.03 | -0.03 |
| 416.49 | -0.22 | -0.22 |
| 390.45 | -0.61 | -0.61 |
| 447.50 | -1.54 | -1.54 |
| 466.55 | 1.05 | 1.05 |
| 478.56 | 0.92 | 0.92 |
| 487.50 | -0.22 | -0.22 |
| 477.53 | 0.91 | 0.91 |
| 456.48 | 0.57 | 0.57 |
| 472.48 | -0.69 | -0.69 |
| 457.47 | -0.23 | -0.23 |
| 470.51 | 0.88 | 0.88 |
| 480.53 | 0.36 | 0.36 |
| 474.47 | 0.52 | 0.52 |
| 392.42 | -2.03 | -2.03 |
| 454.49 | -0.60 | -0.60 |
| 522.49 | 1.33 | 1.33 |
| 392.42 | -2.03 | -2.03 |
| 432.48 | -1.25 | -1.25 |
| 471.50 | -0.09 | -0.09 |
| 358.38 | -1.16 | -1.16 |
| 432.48 | -1.11 | -1.11 |
| 424.44 | -1.69 | -1.69 |
| 471.50 | -0.09 | -0.09 |
| 330.33 | -1.72 | -1.72 |
| 448.50 | 0.12 | 0.12 |
| 486.51 | 0.58 | 0.58 |
| 457.47 | -0.23 | -0.23 |