Basic Information
ID: ALA4418470
Type: Functional
Description: Modulator activity at GPR6 receptor (unknown origin) expressed in CHO-K1 cells assessed as inhibition of constitutive cAMP activity incubated for 45 mins by Eu-cAMP tracer based HTRF Ultra cAMP assay
Format: BAO_0000219
Organism: Homo sapiens
Cell type: CHO-K1
Target: G-protein coupled receptor 6(ALA3714130)
Document: ALA4418317
Modulator activity at GPR6 receptor (unknown origin) expressed in CHO-K1 cells assessed as inhibition of constitutive cAMP activity incubated for 45 mins by Eu-cAMP tracer based HTRF Ultra cAMP assay: 38
Activity Charts
Bioactivity
Activity Types for Assay ALA4418470
EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 499.46 | 5.42 | 5.42 |
| 532.37 | 6.45 | 6.45 |
| 450.45 | 3.82 | 3.82 |
| 493.51 | 5.15 | 5.15 |
| 525.56 | 4.20 | 4.20 |
| 571.42 | 5.64 | 5.64 |
| 579.01 | 5.44 | 5.44 |
| 452.52 | 3.41 | 3.41 |
| 511.53 | 3.77 | 3.77 |
| 515.52 | 4.45 | 4.45 |
| 499.46 | 5.42 | 5.42 |
| 544.56 | 4.78 | 4.78 |
| 532.47 | 5.56 | 5.56 |
| 497.93 | 5.80 | 5.80 |
| 484.50 | 4.21 | 4.21 |
| 477.51 | 5.45 | 5.45 |
| 481.47 | 5.28 | 5.28 |
| 547.48 | 6.04 | 6.04 |
| 521.55 | 4.51 | 4.51 |
| 449.94 | 4.28 | 4.28 |
| 434.53 | 2.99 | 2.99 |
| 507.52 | 4.21 | 4.21 |
| 515.52 | 4.45 | 4.45 |
| 541.56 | 4.90 | 4.90 |
| 492.53 | 4.45 | 4.45 |
| 500.45 | 5.13 | 5.13 |
| 489.48 | 4.41 | 4.41 |
| 535.55 | 3.39 | 3.39 |
| 445.50 | 3.68 | 3.68 |
| 542.38 | 5.91 | 5.91 |
| 483.48 | 3.16 | 3.16 |
| 477.51 | 5.45 | 5.45 |
| 452.52 | 3.41 | 3.41 |
| 463.49 | 3.81 | 3.81 |
| 439.46 | 3.96 | 3.96 |
| 454.48 | 4.37 | 4.37 |
| 477.51 | 5.45 | 5.45 |
| 531.48 | 6.16 | 6.16 |
| 497.93 | 5.80 | 5.80 |
| 499.46 | 5.42 | 5.42 |
| 445.50 | 3.68 | 3.68 |
| 498.92 | 5.19 | 5.19 |
| 421.89 | 3.34 | 3.34 |
| 465.46 | 3.94 | 3.94 |
| 553.57 | 3.58 | 3.58 |
| 492.53 | 4.88 | 4.88 |
| 493.51 | 5.15 | 5.15 |
| 485.47 | 2.69 | 2.69 |
| 527.96 | 5.81 | 5.81 |
| 479.49 | 4.24 | 4.24 |
| 493.51 | 5.15 | 5.15 |
| 504.54 | 5.03 | 5.03 |
| 506.55 | 4.94 | 4.94 |
| 532.37 | 6.45 | 6.45 |
| 535.58 | 4.82 | 4.82 |
| 482.46 | 4.68 | 4.68 |
| 499.46 | 5.42 | 5.42 |
| 535.55 | 4.24 | 4.24 |
| 500.45 | 4.69 | 4.69 |
| 506.55 | 4.96 | 4.96 |
| 485.47 | 2.69 | 2.69 |
| 463.49 | 3.81 | 3.81 |
| 511.96 | 6.11 | 6.11 |
| 421.89 | 3.34 | 3.34 |
| 463.49 | 3.81 | 3.81 |
| 532.37 | 6.45 | 6.45 |
| 458.52 | 2.94 | 2.94 |
| 499.46 | 5.42 | 5.42 |
| 589.62 | 2.38 | 2.38 |
| 491.54 | 5.76 | 5.76 |
| 446.49 | 3.07 | 3.07 |
| 521.55 | 4.51 | 4.51 |
| 497.93 | 5.80 | 5.80 |
| 477.51 | 5.45 | 5.45 |
| 519.59 | 6.44 | 6.44 |
| 542.38 | 5.91 | 5.91 |
| 465.46 | 3.94 | 3.94 |
| 468.46 | 3.27 | 3.27 |
| 498.92 | 5.19 | 5.19 |
| 535.55 | 4.24 | 4.24 |
| 548.59 | 4.98 | 4.98 |
| 511.53 | 3.81 | 3.81 |
| 498.92 | 5.19 | 5.19 |
| 522.55 | 4.33 | 4.33 |
| 531.48 | 6.16 | 6.16 |
| 457.53 | 3.54 | 3.54 |
| 475.52 | 3.68 | 3.68 |
| 449.46 | 4.84 | 4.84 |
| 532.59 | 5.80 | 5.80 |
| 440.45 | 4.06 | 4.06 |
| 493.51 | 5.15 | 5.15 |
| 483.45 | 4.07 | 4.07 |
| 510.54 | 4.37 | 4.37 |
| 529.55 | 5.33 | 5.33 |
| 515.52 | 4.45 | 4.45 |
| 506.55 | 5.21 | 5.21 |
| 541.56 | 4.74 | 4.74 |
| 519.59 | 6.44 | 6.44 |
| 518.56 | 4.71 | 4.71 |
| 525.56 | 4.20 | 4.20 |