Basic Information
ID: ALA4418477
Type: Binding
Description: Inhibition of USP30 (unknown origin) using ubiquitin-rhodamine 110 as substrate preincubated for 15 mins followed by substrate addition and measured after 2 hrs by fluorescence based assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4418477
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 545.66 | 4.60 | 4.60 |
| 523.66 | 3.76 | 3.76 |
| 559.69 | 4.91 | 4.91 |
| 530.65 | 4.29 | 4.29 |
| 587.79 | 5.80 | 5.80 |
| 510.62 | 3.15 | 3.15 |
| 485.65 | 4.47 | 4.47 |
| 543.69 | 5.20 | 5.20 |
| 516.65 | 3.21 | 3.21 |
| 541.76 | 5.89 | 5.89 |
| 510.66 | 3.88 | 3.88 |
| 449.62 | 3.57 | 3.57 |
| 498.58 | 3.28 | 3.28 |
| 480.59 | 3.14 | 3.14 |
| 493.67 | 3.58 | 3.58 |
| 544.68 | 4.60 | 4.60 |
| 486.62 | 3.20 | 3.20 |
| 554.67 | 4.77 | 4.77 |
| 503.64 | 4.61 | 4.61 |
| 529.66 | 4.90 | 4.90 |
| 515.58 | 4.02 | 4.02 |
| 523.61 | 3.44 | 3.44 |
| 503.64 | 4.61 | 4.61 |
| 485.65 | 4.01 | 4.01 |
| 543.69 | 4.83 | 4.83 |
| 559.69 | 4.91 | 4.91 |
| 493.63 | 4.45 | 4.45 |
| 531.64 | 3.69 | 3.69 |
| 472.61 | 2.18 | 2.18 |
| 535.69 | 4.96 | 4.96 |
| 549.74 | 5.41 | 5.41 |
| 471.62 | 3.62 | 3.62 |
| 519.63 | 3.62 | 3.62 |
| 555.70 | 5.30 | 5.30 |
| 471.62 | 3.62 | 3.62 |
| 498.58 | 3.28 | 3.28 |
| 491.70 | 4.74 | 4.74 |
| 485.65 | 4.01 | 4.01 |
| 491.68 | 4.07 | 4.07 |
| 547.65 | 5.04 | 5.04 |
| 536.68 | 4.35 | 4.35 |
| 529.66 | 4.90 | 4.90 |
| 554.67 | 4.77 | 4.77 |
| 497.59 | 3.88 | 3.88 |
| 516.65 | 3.21 | 3.21 |
| 581.59 | 4.78 | 4.78 |
| 537.68 | 4.01 | 4.01 |
| 521.68 | 4.77 | 4.77 |
| 543.69 | 5.20 | 5.20 |
| 518.64 | 4.22 | 4.22 |
| 564.11 | 5.55 | 5.55 |
| 425.55 | 1.76 | 1.76 |
| 535.69 | 4.96 | 4.96 |
| 553.65 | 5.49 | 5.49 |
| 495.65 | 4.70 | 4.70 |
| 497.59 | 3.88 | 3.88 |
| 510.62 | 3.15 | 3.15 |
| 503.64 | 4.15 | 4.15 |
| 535.71 | 5.16 | 5.16 |
| 503.62 | 3.94 | 3.94 |
| 493.63 | 3.99 | 3.99 |
| 510.62 | 3.15 | 3.15 |
| 479.60 | 3.74 | 3.74 |
| 481.58 | 2.53 | 2.53 |
| 535.71 | 5.62 | 5.62 |
| 537.64 | 3.53 | 3.53 |
| 543.69 | 5.20 | 5.20 |
| 527.62 | 3.89 | 3.89 |
| 516.65 | 3.21 | 3.21 |
| 498.58 | 3.28 | 3.28 |
| 477.67 | 4.35 | 4.35 |
| 557.72 | 5.22 | 5.22 |
| 503.64 | 4.61 | 4.61 |
| 549.74 | 5.55 | 5.55 |
| 519.62 | 4.49 | 4.49 |
| 545.66 | 4.60 | 4.60 |
| 564.11 | 5.55 | 5.55 |
| 516.65 | 3.21 | 3.21 |
| 547.65 | 5.04 | 5.04 |
| 520.10 | 4.66 | 4.66 |
| 543.69 | 5.29 | 5.29 |
| 500.58 | 2.74 | 2.74 |
| 510.66 | 4.34 | 4.34 |
| 499.68 | 4.32 | 4.32 |
| 564.11 | 5.55 | 5.55 |
| 521.63 | 4.75 | 4.75 |
| 439.58 | 2.15 | 2.15 |
| 573.69 | 5.55 | 5.55 |
| 486.64 | 3.87 | 3.87 |
| 571.69 | 5.41 | 5.41 |