Basic Information
ID: ALA4418508
Type: Binding
Description: Inhibition of recombinant FLAG-tagged EML4-ALK fusion protein (unknown origin) expressed in mouse BA/F3 cells assessed as inhibition of cell growth incubated for 2 days by alamar blue dye based assay
Format: BAO_0000219
Organism: Homo sapiens
Target: EML4-ALK(ALA3883330)
Document: ALA4418479
Inhibition of recombinant FLAG-tagged EML4-ALK fusion protein (unknown origin) expressed in mouse BA/F3 cells assessed as inhibition of cell growth incubated for 2 days by alamar blue dye based assay: 38
Activity Charts
Bioactivity
Activity Types for Assay ALA4418508
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 552.72 | 2.70 | 2.70 |
| 433.53 | 2.00 | 2.00 |
| 447.56 | 2.39 | 2.39 |
| 566.75 | 2.82 | 2.82 |
| 453.59 | 2.35 | 2.35 |
| 409.49 | 2.48 | 2.48 |
| 566.75 | 2.82 | 2.82 |
| 536.73 | 2.81 | 2.81 |
| 467.62 | 2.91 | 2.91 |
| 521.59 | 3.37 | 3.37 |
| 483.62 | 2.36 | 2.36 |
| 440.55 | 2.43 | 2.43 |
| 604.72 | 3.83 | 3.83 |
| 467.62 | 2.66 | 2.66 |
| 550.75 | 3.12 | 3.12 |
| 452.60 | 3.41 | 3.41 |
| 618.75 | 4.39 | 4.39 |
| 481.65 | 3.05 | 3.05 |
| 564.78 | 3.51 | 3.51 |
| 535.62 | 3.76 | 3.76 |
| 495.67 | 3.44 | 3.44 |
| 580.78 | 3.21 | 3.21 |
| 564.78 | 3.51 | 3.51 |
| 536.73 | 3.00 | 3.00 |
| 535.74 | 2.57 | 2.57 |
| 557.14 | 3.21 | 3.21 |
| 549.77 | 2.91 | 2.91 |
| 439.56 | 2.22 | 2.22 |
| 522.70 | 2.69 | 2.69 |
| 536.73 | 3.25 | 3.25 |
| 457.55 | 2.36 | 2.36 |
| 483.62 | 2.79 | 2.79 |
| 453.59 | 2.79 | 2.79 |
| 536.73 | 3.00 | 3.00 |
| 483.62 | 2.36 | 2.36 |
| 453.59 | 2.35 | 2.35 |
| 487.61 | 3.50 | 3.50 |
| 592.83 | 4.15 | 4.15 |
| 578.81 | 3.90 | 3.90 |
| 561.65 | 4.15 | 4.15 |
| 592.83 | 4.15 | 4.15 |
| 578.81 | 3.90 | 3.90 |
| 342.45 | 2.16 | 2.16 |