Basic Information
ID: ALA4418514
Type: Binding
Description: Inhibition of N-terminal GST-tagged human FLT3 cytoplasmic domain (564 to 993 amino acids) expressed in baculovirus expression system pre-incubated before peptide substrate and ATP addition and measured after 30 mins
Format: BAO_0000019
Organism: Homo sapiens
Target: Tyrosine-protein kinase receptor FLT3(ALA1974)
Document: ALA4418479
Inhibition of N-terminal GST-tagged human FLT3 cytoplasmic domain (564 to 993 amino acids) expressed in baculovirus expression system pre-incubated before peptide substrate and ATP addition and measured after 30 mins: 38
Activity Charts
Bioactivity
Activity Types for Assay ALA4418514
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 599.69 | 2.79 | 2.79 |
| 680.85 | 3.51 | 3.51 |
| 569.66 | 2.35 | 2.35 |
| 583.69 | 2.91 | 2.91 |
| 573.63 | 2.36 | 2.36 |
| 638.77 | 2.69 | 2.69 |
| 734.82 | 4.39 | 4.39 |
| 652.80 | 2.81 | 2.81 |
| 666.82 | 3.12 | 3.12 |
| 652.80 | 3.25 | 3.25 |
| 668.80 | 2.70 | 2.70 |
| 680.85 | 3.51 | 3.51 |
| 611.74 | 3.44 | 3.44 |
| 720.79 | 3.83 | 3.83 |
| 673.21 | 3.21 | 3.21 |
| 652.80 | 3.00 | 3.00 |
| 652.80 | 3.00 | 3.00 |
| 569.66 | 2.79 | 2.79 |