Basic Information
ID: ALA4418545
Type: Binding
Description: Inhibition of TMPRSS4 serine protease domain (Val205 to Leu437 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) at 10 uM using Z-Phe-Arg7-amido-4-methylcoumarin hydrochloride substrate measured at 5 mins interval for 150 mins by fluorescence based assay relative to control
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4418545
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 349.23 | 4.68 | 4.68 |
| 254.70 | 2.75 | 2.75 |
| 248.67 | 2.69 | 2.69 |
| 383.68 | 5.34 | 5.34 |
| 272.69 | 3.17 | 3.17 |
| 315.68 | 4.32 | 4.32 |
| 247.68 | 3.30 | 3.30 |
| 315.68 | 4.32 | 4.32 |
| 275.74 | 3.91 | 3.91 |
| 272.69 | 3.17 | 3.17 |
| 316.57 | 4.60 | 4.60 |
| 329.70 | 4.63 | 4.63 |
| 350.12 | 4.97 | 4.97 |
| 333.67 | 4.46 | 4.46 |
| 394.57 | 5.08 | 5.08 |
| 333.67 | 4.46 | 4.46 |
| 350.12 | 4.97 | 4.97 |
| 340.69 | 4.19 | 4.19 |
| 345.70 | 4.33 | 4.33 |
| 351.02 | 5.26 | 5.26 |
| 363.26 | 4.99 | 4.99 |
| 367.22 | 4.82 | 4.82 |
| 428.13 | 5.44 | 5.44 |
| 379.26 | 4.69 | 4.69 |
| 418.12 | 5.99 | 5.99 |
| 394.23 | 4.59 | 4.59 |
| 425.71 | 5.56 | 5.56 |
| 473.80 | 7.21 | 7.21 |
| 397.70 | 5.01 | 5.01 |
| 383.68 | 5.34 | 5.34 |
| 383.68 | 5.34 | 5.34 |
| 394.57 | 5.08 | 5.08 |
| 413.70 | 5.34 | 5.34 |
| 462.57 | 6.10 | 6.10 |
| 384.66 | 4.73 | 4.73 |
| 400.28 | 5.23 | 5.23 |
| 273.68 | 2.56 | 2.56 |
| 316.67 | 3.71 | 3.71 |
| 283.11 | 3.35 | 3.35 |
| 283.11 | 3.35 | 3.35 |
| 249.66 | 2.09 | 2.09 |
| 298.73 | 3.85 | 3.85 |
| 383.68 | 5.34 | 5.34 |
| 383.68 | 5.34 | 5.34 |
| 374.24 | 4.55 | 4.55 |
| 392.26 | 3.78 | 3.78 |
| 277.71 | 2.70 | 2.70 |
| 268.73 | 3.06 | 3.06 |
| 322.69 | 3.77 | 3.77 |
| 397.70 | 5.64 | 5.64 |
| 331.78 | 3.82 | 3.82 |
| 351.11 | 4.37 | 4.37 |
| 320.63 | 3.25 | 3.25 |
| 283.11 | 3.35 | 3.35 |
| 360.68 | 4.22 | 4.22 |
| 256.71 | 1.88 | 1.88 |
| 394.57 | 5.08 | 5.08 |
| 364.25 | 4.26 | 4.26 |
| 495.75 | 7.28 | 7.28 |
| 330.80 | 4.42 | 4.42 |
| 323.68 | 3.17 | 3.17 |
| 417.23 | 5.70 | 5.70 |
| 268.73 | 3.06 | 3.06 |
| 366.56 | 5.57 | 5.57 |
| 307.14 | 3.82 | 3.82 |
| 251.67 | 2.03 | 2.03 |
| 418.12 | 5.99 | 5.99 |
| 406.28 | 4.64 | 4.64 |
| 418.12 | 5.99 | 5.99 |
| 399.29 | 5.84 | 5.84 |
| 381.89 | 3.36 | 3.36 |
| 308.79 | 3.63 | 3.63 |
| 283.11 | 3.35 | 3.35 |
| 252.66 | 1.72 | 1.72 |
| 282.75 | 3.37 | 3.37 |