Basic Information
ID: ALA4418553
Type: Binding
Description: Inhibition of N-terminal GST tagged human recombinant PASK kinase domain (879 to 1323 residues) expressed in insect cells pre-incubated in presence myelin basic protein before addition of [33P]-ATP and further incubated for 120 mins by scintillation counting based ATP radiochemical assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4418553
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 347.42 | 4.38 | 4.38 |
| 443.93 | 6.03 | 6.03 |
| 335.36 | 2.83 | 2.83 |
| 362.43 | 3.14 | 3.14 |
| 307.35 | 3.82 | 3.82 |
| 412.45 | 3.11 | 3.11 |
| 479.46 | 4.74 | 4.74 |
| 461.53 | 4.87 | 4.87 |
| 347.42 | 4.38 | 4.38 |
| 333.39 | 3.99 | 3.99 |
| 461.92 | 6.17 | 6.17 |
| 461.92 | 6.17 | 6.17 |
| 457.51 | 5.53 | 5.53 |
| 429.46 | 3.86 | 3.86 |
| 495.48 | 6.54 | 6.54 |
| 492.62 | 6.10 | 6.10 |
| 410.44 | 4.16 | 4.16 |
| 440.53 | 2.86 | 2.86 |
| 381.44 | 5.08 | 5.08 |
| 321.38 | 3.84 | 3.84 |
| 319.36 | 3.59 | 3.59 |
| 363.42 | 3.61 | 3.61 |
| 349.39 | 2.96 | 2.96 |
| 333.39 | 3.98 | 3.98 |
| 339.37 | 3.98 | 3.98 |
| 351.41 | 3.85 | 3.85 |
| 387.36 | 4.53 | 4.53 |
| 411.46 | 5.09 | 5.09 |
| 357.36 | 4.12 | 4.12 |
| 355.83 | 4.49 | 4.49 |
| 347.42 | 4.37 | 4.37 |
| 351.38 | 4.12 | 4.12 |
| 351.38 | 4.12 | 4.12 |
| 365.41 | 4.51 | 4.51 |
| 365.39 | 3.57 | 3.57 |
| 395.43 | 4.00 | 4.00 |
| 379.44 | 4.76 | 4.76 |
| 365.41 | 4.37 | 4.37 |
| 379.42 | 3.61 | 3.61 |
| 377.40 | 3.71 | 3.71 |
| 360.42 | 4.32 | 4.32 |
| 322.37 | 3.23 | 3.23 |
| 361.41 | 3.49 | 3.49 |
| 361.40 | 4.59 | 4.59 |
| 478.47 | 5.34 | 5.34 |
| 411.47 | 3.72 | 3.72 |
| 444.92 | 4.98 | 4.98 |
| 348.41 | 2.75 | 2.75 |
| 334.38 | 2.40 | 2.40 |
| 410.48 | 4.32 | 4.32 |
| 477.49 | 6.40 | 6.40 |
| 444.92 | 4.98 | 4.98 |
| 440.50 | 4.33 | 4.33 |
| 443.93 | 6.03 | 6.03 |
| 333.39 | 3.99 | 3.99 |
| 409.49 | 5.38 | 5.38 |
| 479.46 | 4.74 | 4.74 |