Basic Information
ID: ALA4418659
Type: Binding
Description: Inhibition of GST tagged human recombinant PASK kinase domain expressed in Baculovirus based system incubated for 2 hrs using ATP and Ulight-peptide by TR-FRET assay
Format: BAO_0000019
Organism: Homo sapiens
Target: PAS domain-containing serine/threonine-protein kinase(ALA6054)
Document: ALA4418486
Inhibition of GST tagged human recombinant PASK kinase domain expressed in Baculovirus based system incubated for 2 hrs using ATP and Ulight-peptide by TR-FRET assay: 38
Activity Charts
Bioactivity
Activity Types for Assay ALA4418659
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 374.40 | 3.28 | 3.28 |
| 322.28 | 2.07 | 2.07 |
| 336.31 | 2.38 | 2.38 |
| 336.31 | 2.38 | 2.38 |
| 336.31 | 2.38 | 2.38 |
| 333.31 | 1.92 | 1.92 |
| 347.34 | 2.18 | 2.18 |
| 327.73 | 2.70 | 2.70 |
| 341.76 | 3.01 | 3.01 |
| 343.73 | 2.41 | 2.41 |
| 357.76 | 2.71 | 2.71 |
| 333.31 | 1.92 | 1.92 |
| 360.38 | 3.02 | 3.02 |
| 360.38 | 3.02 | 3.02 |
| 350.33 | 2.64 | 2.64 |
| 347.34 | 2.18 | 2.18 |
| 350.33 | 2.64 | 2.64 |
| 356.77 | 3.32 | 3.32 |
| 356.77 | 3.32 | 3.32 |
| 342.74 | 3.01 | 3.01 |
| 346.35 | 2.71 | 2.71 |
| 370.80 | 3.71 | 3.71 |
| 332.32 | 2.53 | 2.53 |
| 318.30 | 2.22 | 2.22 |
| 376.45 | 3.49 | 3.49 |
| 362.42 | 3.18 | 3.18 |
| 374.40 | 3.28 | 3.28 |
| 360.38 | 3.02 | 3.02 |
| 361.37 | 2.42 | 2.42 |
| 359.39 | 2.46 | 2.46 |
| 396.41 | 3.87 | 3.87 |
| 356.77 | 3.40 | 3.40 |
| 384.82 | 3.96 | 3.96 |
| 354.34 | 3.19 | 3.19 |
| 424.77 | 4.25 | 4.25 |
| 410.74 | 4.21 | 4.21 |
| 358.81 | 3.48 | 3.48 |
| 412.48 | 4.34 | 4.34 |
| 408.87 | 4.63 | 4.63 |
| 374.40 | 3.33 | 3.33 |
| 361.37 | 2.42 | 2.42 |
| 334.36 | 3.56 | 3.56 |
| 392.80 | 4.16 | 4.16 |
| 370.80 | 3.71 | 3.71 |
| 326.74 | 3.31 | 3.31 |
| 312.72 | 3.00 | 3.00 |
| 347.34 | 2.11 | 2.11 |
| 392.80 | 4.16 | 4.16 |
| 355.79 | 2.75 | 2.75 |
| 356.77 | 3.32 | 3.32 |
| 359.39 | 2.46 | 2.46 |
| 355.79 | 2.75 | 2.75 |
| 345.37 | 2.45 | 2.45 |
| 372.84 | 3.78 | 3.78 |
| 328.78 | 3.47 | 3.47 |
| 342.81 | 3.77 | 3.77 |
| 396.41 | 3.87 | 3.87 |
| 397.22 | 4.80 | 4.80 |
| 333.31 | 2.79 | 2.79 |
| 418.84 | 4.67 | 4.67 |
| 422.45 | 4.38 | 4.38 |
| 369.81 | 3.24 | 3.24 |
| 339.79 | 3.23 | 3.23 |
| 373.42 | 2.94 | 2.94 |
| 355.79 | 3.05 | 3.05 |
| 346.18 | 3.39 | 3.39 |
| 331.34 | 1.97 | 1.97 |
| 362.42 | 3.01 | 3.01 |
| 347.34 | 1.93 | 1.93 |
| 319.28 | 1.92 | 1.92 |
| 332.32 | 2.23 | 2.23 |
| 383.84 | 3.53 | 3.53 |
| 353.36 | 2.63 | 2.63 |
| 339.33 | 2.24 | 2.24 |
| 360.80 | 2.03 | 2.03 |
| 346.77 | 1.64 | 1.64 |
| 345.37 | 1.98 | 1.98 |
| 359.39 | 2.76 | 2.76 |
| 373.42 | 2.77 | 2.77 |
| 360.38 | 3.02 | 3.02 |
| 360.38 | 3.02 | 3.02 |
| 373.42 | 3.02 | 3.02 |
| 314.73 | 2.42 | 2.42 |
| 347.33 | 3.10 | 3.10 |
| 347.33 | 3.10 | 3.10 |
| 425.75 | 3.64 | 3.64 |
| 359.39 | 2.46 | 2.46 |
| 437.81 | 4.17 | 4.17 |
| 374.23 | 3.88 | 3.88 |
| 423.78 | 3.68 | 3.68 |
| 351.32 | 1.82 | 1.82 |
| 360.20 | 3.40 | 3.40 |
| 389.38 | 1.97 | 1.97 |
| 362.18 | 3.35 | 3.35 |
| 377.26 | 4.43 | 4.43 |
| 377.26 | 4.43 | 4.43 |
| 374.40 | 3.41 | 3.41 |
| 374.40 | 3.33 | 3.33 |
| 332.32 | 0.93 | 0.93 |
| 374.40 | 3.33 | 3.33 |