Basic Information
ID: ALA4418720
Type: Toxicity
Description: Toxicity in 4 weeks old Abca4(-/-)/Rdh8 (-/-) mouse model of intense light-induced retinal degeneration at 1 mg dosed via gavage under dark for 24 hrs before exposure to 10000 lux bright light for 1 hr by SDOCT and ERG analysis
Format: BAO_0000218
Organism: Mus musculus
Target: ADMET(ALA612558)
Document: ALA4418488
Toxicity in 4 weeks old Abca4(-/-)/Rdh8 (-/-) mouse model of intense light-induced retinal degeneration at 1 mg dosed via gavage under dark for 24 hrs before exposure to 10000 lux bright light for 1 hr by SDOCT and ERG analysis: 38
Activity Charts
Bioactivity
Activity Types for Assay ALA4418720
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 327.56 | 6.50 | 6.50 |
| 285.48 | 5.48 | 5.48 |
| 369.43 | 6.26 | 6.26 |
| 281.44 | 5.13 | 5.13 |
| 335.49 | 5.60 | 5.60 |
| 245.41 | 4.53 | 4.53 |
| 243.39 | 4.45 | 4.45 |
| 299.50 | 5.87 | 5.87 |
| 347.46 | 4.96 | 4.96 |
| 257.42 | 4.70 | 4.70 |
| 285.48 | 5.48 | 5.48 |
| 305.47 | 5.73 | 5.73 |