Assay Report Card

Basic Information

ID: ALA4418721

Type: ADME

Description: Drug metabolism in 4 weeks old Abca4(-/-)/Rdh8 (-/-) mouse model of intense light-induced retinal degeneration assessed as accumulation of intense amide peaks in liver at 1 mg dosed via gavage under dark for 24 hrs before exposure to 10000 lux bright light for 1 hr by SDOCT and ERG analysis

Organism: Mus musculus

Tissue: Liver

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
285.485.485.48
281.445.135.13
305.475.735.73