Basic Information
ID: ALA4418730
Type: Functional
Description: Protective effect against intense light-induced retinal degeneration in 4 weeks old Abca4(-/-)/Rdh8 (-/-) mouse assessed as inhibition of rate of visual chromophore recovery by measuring 11-cis- retinal level in eye at 0.5 mg dosed via gavage under dark for 24 hrs before exposure to 10000 lux bright light for 1 hr by HPLC analysis relative to control
Format: BAO_0000218
Organism: Mus musculus
Target: Mus musculus(ALA375)
Document: ALA4418488
Protective effect against intense light-induced retinal degeneration in 4 weeks old Abca4(-/-)/Rdh8 (-/-) mouse assessed as inhibition of rate of visual chromophore recovery by measuring 11-cis- retinal level in eye at 0.5 mg dosed via gavage under dark for 24 hrs before exposure to 10000 lux bright light for 1 hr by HPLC analysis relative to control: 38
Activity Charts
Bioactivity
Activity Types for Assay ALA4418730
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 285.48 | 5.48 | 5.48 |