Assay Report Card

Basic Information

ID: ALA4418730

Type: Functional

Description: Protective effect against intense light-induced retinal degeneration in 4 weeks old Abca4(-/-)/Rdh8 (-/-) mouse assessed as inhibition of rate of visual chromophore recovery by measuring 11-cis- retinal level in eye at 0.5 mg dosed via gavage under dark for 24 hrs before exposure to 10000 lux bright light for 1 hr by HPLC analysis relative to control

Organism: Mus musculus

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
285.485.485.48