Basic Information
ID: ALA4418735
Type: Functional
Description: Protective effect against intense light-induced retinal degeneration in 4 weeks old Abca4(-/-)/Rdh8 (-/-) mouse assessed as inhibition of rate of visual chromophore recovery by measuring 11-cis- retinal level per eye at 0.1 mg dosed via gavage under dark for 24 hrs before exposure to 10000 lux bright light for 1 hr followed by exposure to dark for 7 days by HPLC analysis (Rvb = 301+/- 8 pmol/eye)
Organism: Mus musculus
Activity Charts
Bioactivity
Activity Types for Assay ALA4418735
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 285.48 | 5.48 | 5.48 |