Basic Information
ID: ALA4418796
Type: Binding
Description: Inhibition of human LOXL2 expressed in CHO cells assessed as reduction in amine oxidase activity in presence of 1,5-Diaminopentane incubated for 2 hrs by Amplex red based fluorescence assay
Format: BAO_0000219
Organism: Homo sapiens
Cell type: CHO
Target: Lysyl oxidase homolog 2(ALA3714029)
Document: ALA4418491
Inhibition of human LOXL2 expressed in CHO cells assessed as reduction in amine oxidase activity in presence of 1,5-Diaminopentane incubated for 2 hrs by Amplex red based fluorescence assay: 38
Activity Charts
Bioactivity
Activity Types for Assay ALA4418796
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 399.88 | 2.21 | 2.21 |
| 361.81 | -0.73 | -0.73 |
| 290.54 | 2.01 | 2.01 |
| 312.75 | 0.72 | 0.72 |
| 322.79 | 1.88 | 1.88 |
| 354.80 | 2.50 | 2.50 |
| 436.90 | 4.08 | 4.08 |
| 285.68 | 0.72 | 0.72 |
| 331.80 | 2.87 | 2.87 |
| 373.86 | 4.05 | 4.05 |
| 341.79 | 2.68 | 2.68 |
| 290.54 | 2.01 | 2.01 |
| 312.75 | 0.72 | 0.72 |
| 235.67 | 1.23 | 1.23 |
| 347.80 | 2.71 | 2.71 |
| 303.75 | 3.04 | 3.04 |
| 352.77 | 0.80 | 0.80 |
| 360.80 | 2.27 | 2.27 |
| 371.87 | 2.58 | 2.58 |
| 283.75 | 2.29 | 2.29 |
| 347.80 | 2.71 | 2.71 |
| 342.83 | 3.34 | 3.34 |
| 342.75 | 0.41 | 0.41 |
| 277.71 | 1.44 | 1.44 |
| 360.24 | 0.42 | 0.42 |
| 317.77 | 2.83 | 2.83 |
| 322.75 | 0.50 | 0.50 |
| 288.73 | 2.31 | 2.31 |
| 298.73 | -0.03 | -0.03 |
| 366.80 | 0.89 | 0.89 |
| 292.73 | 1.05 | 1.05 |
| 235.67 | 1.23 | 1.23 |
| 354.80 | 2.50 | 2.50 |
| 235.67 | 1.23 | 1.23 |
| 384.82 | 2.41 | 2.41 |
| 385.77 | 3.85 | 3.85 |
| 342.75 | 0.41 | 0.41 |
| 317.77 | 2.83 | 2.83 |
| 293.75 | 1.37 | 1.37 |
| 287.75 | 2.92 | 2.92 |
| 349.78 | 0.27 | 0.27 |
| 342.75 | 0.41 | 0.41 |
| 360.82 | 0.03 | 0.03 |
| 368.82 | 3.38 | 3.38 |
| 368.82 | 3.18 | 3.18 |
| 292.73 | 1.05 | 1.05 |
| 290.54 | 2.01 | 2.01 |
| 265.70 | 1.26 | 1.26 |
| 371.74 | 4.06 | 4.06 |
| 227.65 | 0.96 | 0.96 |
| 296.75 | 0.82 | 0.82 |
| 282.73 | 0.95 | 0.95 |
| 227.65 | 0.96 | 0.96 |
| 241.67 | 1.26 | 1.26 |
| 347.80 | 2.84 | 2.84 |
| 366.80 | 0.89 | 0.89 |
| 436.90 | 4.08 | 4.08 |
| 291.74 | 1.65 | 1.65 |
| 422.87 | 4.30 | 4.30 |
| 241.67 | 1.26 | 1.26 |
| 277.71 | 1.44 | 1.44 |
| 338.79 | 3.47 | 3.47 |
| 363.81 | 0.60 | 0.60 |
| 317.77 | 2.83 | 2.83 |
| 353.30 | 2.18 | 2.18 |
| 333.77 | 3.05 | 3.05 |
| 368.82 | 2.56 | 2.56 |
| 288.73 | 2.31 | 2.31 |
| 265.70 | 1.26 | 1.26 |