Basic Information
ID: ALA4418812
Type: Binding
Description: Inhibition of C-terminal FLAG-6x-His epitope tagged and N-terminal human RAGE signal sequence tagged human BMP1 (121 to 721 amino acids) expressed in CHO-E1 cells pre-incubated for 10 mins before promyostatin peptide substrate addition and measured after 30 mins using 50 nM BMP1 by FRET based assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4418812
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 716.79 | 3.74 | 3.74 |
| 669.67 | 4.32 | 4.32 |
| 828.87 | 3.78 | 3.78 |
| 861.90 | 3.39 | 3.39 |
| 744.74 | 4.23 | 4.23 |
| 766.80 | 4.02 | 4.02 |
| 803.83 | 3.59 | 3.59 |
| 798.77 | 3.52 | 3.52 |
| 941.89 | 4.36 | 4.36 |
| 782.76 | 2.78 | 2.78 |
| 730.81 | 4.13 | 4.13 |
| 819.82 | 3.22 | 3.22 |
| 688.78 | 3.89 | 3.89 |
| 714.75 | 4.96 | 4.96 |
| 850.80 | 4.92 | 4.92 |
| 768.79 | 4.46 | 4.46 |
| 672.67 | 4.55 | 4.55 |
| 808.88 | 5.14 | 5.14 |
| 770.82 | 4.30 | 4.30 |
| 660.72 | 3.11 | 3.11 |
| 513.64 | 4.69 | 4.69 |
| 728.74 | 3.99 | 3.99 |
| 665.63 | 3.37 | 3.37 |
| 750.80 | 4.32 | 4.32 |
| 689.67 | 4.60 | 4.60 |
| 856.88 | 4.60 | 4.60 |
| 744.75 | 2.56 | 2.56 |
| 762.77 | 3.17 | 3.17 |
| 558.63 | 2.82 | 2.82 |
| 742.76 | 3.99 | 3.99 |
| 756.79 | 3.99 | 3.99 |
| 688.78 | 3.59 | 3.59 |
| 651.69 | 4.28 | 4.28 |
| 715.69 | 3.93 | 3.93 |
| 533.63 | 4.96 | 4.96 |
| 795.80 | 3.09 | 3.09 |
| 849.93 | 4.15 | 4.15 |
| 732.78 | 3.24 | 3.24 |
| 667.69 | 3.86 | 3.86 |
| 781.77 | 3.92 | 3.92 |
| 663.55 | 2.38 | 2.38 |
| 788.85 | 3.98 | 3.98 |
| 731.80 | 3.68 | 3.68 |
| 744.74 | 4.22 | 4.22 |
| 824.79 | 3.00 | 3.00 |
| 673.66 | 3.86 | 3.86 |
| 793.87 | 4.82 | 4.82 |
| 577.68 | 4.97 | 4.97 |
| 838.86 | 4.21 | 4.21 |
| 766.76 | 3.08 | 3.08 |
| 586.69 | 3.06 | 3.06 |
| 762.80 | 3.99 | 3.99 |
| 816.82 | 4.23 | 4.23 |
| 687.68 | 4.17 | 4.17 |
| 646.68 | 4.86 | 4.86 |
| 752.77 | 3.72 | 3.72 |
| 826.81 | 3.09 | 3.09 |
| 804.77 | 5.03 | 5.03 |
| 767.75 | 2.47 | 2.47 |
| 832.86 | 2.78 | 2.78 |
| 781.77 | 3.47 | 3.47 |
| 796.83 | 4.03 | 4.03 |
| 774.81 | 4.28 | 4.28 |
| 778.86 | 5.14 | 5.14 |
| 719.70 | 1.58 | 1.58 |
| 750.80 | 3.94 | 3.94 |
| 501.58 | 3.75 | 3.75 |
| 544.65 | 3.29 | 3.29 |
| 744.88 | 5.14 | 5.14 |
| 729.76 | 5.29 | 5.29 |
| 736.78 | 4.01 | 4.01 |
| 735.77 | 4.47 | 4.47 |
| 877.90 | 3.09 | 3.09 |
| 758.76 | 4.54 | 4.54 |
| 814.89 | 4.33 | 4.33 |
| 853.93 | 4.14 | 4.14 |
| 652.68 | 3.83 | 3.83 |
| 802.84 | 4.20 | 4.20 |
| 808.84 | 4.20 | 4.20 |
| 747.76 | 2.35 | 2.35 |
| 810.81 | 3.39 | 3.39 |
| 693.77 | 5.59 | 5.59 |
| 714.71 | 4.22 | 4.22 |
| 781.77 | 2.66 | 2.66 |
| 529.63 | 4.53 | 4.53 |
| 717.73 | 5.42 | 5.42 |
| 823.85 | 3.88 | 3.88 |
| 784.79 | 4.16 | 4.16 |
| 766.80 | 3.90 | 3.90 |
| 801.85 | 4.80 | 4.80 |
| 826.83 | 4.34 | 4.34 |
| 840.88 | 3.40 | 3.40 |
| 487.55 | 3.88 | 3.88 |
| 717.77 | 3.29 | 3.29 |
| 796.83 | 4.03 | 4.03 |
| 857.83 | 2.70 | 2.70 |
| 704.73 | 1.96 | 1.96 |
| 841.92 | 3.84 | 3.84 |
| 756.79 | 4.95 | 4.95 |
| 834.80 | 5.04 | 5.04 |
| 757.73 | 2.35 | 2.35 |
| 671.68 | 4.09 | 4.09 |
| 796.85 | 5.27 | 5.27 |
| 778.82 | 4.90 | 4.90 |
| 857.93 | 4.75 | 4.75 |
| 790.85 | 4.30 | 4.30 |
| 802.84 | 4.20 | 4.20 |
| 795.80 | 3.12 | 3.12 |
| 708.77 | 4.15 | 4.15 |
| 746.81 | 3.72 | 3.72 |
| 732.78 | 4.11 | 4.11 |
| 772.65 | 1.30 | 1.30 |
| 744.75 | 2.42 | 2.42 |
| 705.75 | 6.95 | 6.95 |
| 843.91 | 3.41 | 3.41 |
| 853.84 | 3.14 | 3.14 |
| 835.91 | 3.84 | 3.84 |
| 765.82 | 4.02 | 4.02 |
| 547.65 | 4.88 | 4.88 |
| 865.89 | 2.91 | 2.91 |
| 835.91 | 4.80 | 4.80 |
| 753.78 | 5.14 | 5.14 |
| 954.92 | 3.57 | 3.57 |
| 879.92 | 3.22 | 3.22 |
| 761.78 | 2.74 | 2.74 |
| 653.67 | 4.25 | 4.25 |
| 760.83 | 4.76 | 4.76 |
| 529.63 | 5.05 | 5.05 |
| 638.66 | 3.43 | 3.43 |
| 818.80 | 5.34 | 5.34 |
| 780.78 | 3.39 | 3.39 |
| 697.68 | 3.86 | 3.86 |
| 816.82 | 4.23 | 4.23 |
| 785.78 | 5.86 | 5.86 |
| 832.90 | 3.86 | 3.86 |
| 785.76 | 2.68 | 2.68 |
| 796.78 | 3.09 | 3.09 |
| 839.94 | 4.61 | 4.61 |
| 865.81 | 3.91 | 3.91 |
| 810.77 | 2.77 | 2.77 |
| 768.79 | 4.46 | 4.46 |
| 760.83 | 4.76 | 4.76 |
| 760.79 | 3.20 | 3.20 |
| 657.66 | 4.16 | 4.16 |