Basic Information
ID: ALA4418814
Type: Binding
Description: Inhibition of C-terminal Avi-6x-His epitope tagged and N-terminal human RAGE signal sequence tagged recombinant human TLL2 (26 to 1015 amino acids) expressed in CHOE1A cells incubated for 60 mins with promyostatin peptide substrate by FRET based assay
Format: BAO_0000219
Organism: Homo sapiens
Target: Tolloid-like protein 2(ALA4295995)
Document: ALA4418493
Inhibition of C-terminal Avi-6x-His epitope tagged and N-terminal human RAGE signal sequence tagged recombinant human TLL2 (26 to 1015 amino acids) expressed in CHOE1A cells incubated for 60 mins with promyostatin peptide substrate by FRET based assay: 38
Activity Charts
Bioactivity
Activity Types for Assay ALA4418814
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 716.79 | 3.74 | 3.74 |
| 828.87 | 3.78 | 3.78 |
| 861.90 | 3.39 | 3.39 |
| 766.80 | 4.02 | 4.02 |
| 798.77 | 3.52 | 3.52 |
| 782.76 | 2.78 | 2.78 |
| 730.81 | 4.13 | 4.13 |
| 819.82 | 3.22 | 3.22 |
| 714.75 | 4.96 | 4.96 |
| 768.79 | 4.46 | 4.46 |
| 672.67 | 4.55 | 4.55 |
| 808.88 | 5.14 | 5.14 |
| 770.82 | 4.30 | 4.30 |
| 728.74 | 3.99 | 3.99 |
| 750.80 | 4.32 | 4.32 |
| 689.67 | 4.60 | 4.60 |
| 856.88 | 4.60 | 4.60 |
| 744.75 | 2.56 | 2.56 |
| 762.77 | 3.17 | 3.17 |
| 558.63 | 2.82 | 2.82 |
| 742.76 | 3.99 | 3.99 |
| 756.79 | 3.99 | 3.99 |
| 651.69 | 4.28 | 4.28 |
| 715.69 | 3.93 | 3.93 |
| 795.80 | 3.09 | 3.09 |
| 849.93 | 4.15 | 4.15 |
| 732.78 | 3.24 | 3.24 |
| 667.69 | 3.86 | 3.86 |
| 663.55 | 2.38 | 2.38 |
| 788.85 | 3.98 | 3.98 |
| 731.80 | 3.68 | 3.68 |
| 744.74 | 4.22 | 4.22 |
| 824.79 | 3.00 | 3.00 |
| 673.66 | 3.86 | 3.86 |
| 793.87 | 4.82 | 4.82 |
| 577.68 | 4.97 | 4.97 |
| 838.86 | 4.21 | 4.21 |
| 766.76 | 3.08 | 3.08 |
| 586.69 | 3.06 | 3.06 |
| 762.80 | 3.99 | 3.99 |
| 687.68 | 4.17 | 4.17 |
| 826.81 | 3.09 | 3.09 |
| 767.75 | 2.47 | 2.47 |
| 832.86 | 2.78 | 2.78 |
| 781.77 | 3.47 | 3.47 |
| 796.83 | 4.03 | 4.03 |
| 774.81 | 4.28 | 4.28 |
| 778.86 | 5.14 | 5.14 |
| 719.70 | 1.58 | 1.58 |
| 750.80 | 3.94 | 3.94 |
| 501.58 | 3.75 | 3.75 |
| 544.65 | 3.29 | 3.29 |
| 729.76 | 5.29 | 5.29 |
| 736.78 | 4.01 | 4.01 |
| 735.77 | 4.47 | 4.47 |
| 877.90 | 3.09 | 3.09 |
| 814.89 | 4.33 | 4.33 |
| 853.93 | 4.14 | 4.14 |
| 652.68 | 3.83 | 3.83 |
| 808.84 | 4.20 | 4.20 |
| 747.76 | 2.35 | 2.35 |
| 810.81 | 3.39 | 3.39 |
| 693.77 | 5.59 | 5.59 |
| 781.77 | 2.66 | 2.66 |
| 529.63 | 4.53 | 4.53 |
| 717.73 | 5.42 | 5.42 |
| 823.85 | 3.88 | 3.88 |
| 826.83 | 4.34 | 4.34 |
| 796.83 | 4.03 | 4.03 |
| 756.79 | 4.95 | 4.95 |
| 757.73 | 2.35 | 2.35 |
| 671.68 | 4.09 | 4.09 |
| 796.85 | 5.27 | 5.27 |
| 778.82 | 4.90 | 4.90 |
| 857.93 | 4.75 | 4.75 |
| 790.85 | 4.30 | 4.30 |
| 795.80 | 3.12 | 3.12 |
| 746.81 | 3.72 | 3.72 |
| 732.78 | 4.11 | 4.11 |
| 772.65 | 1.30 | 1.30 |
| 744.75 | 2.42 | 2.42 |
| 853.84 | 3.14 | 3.14 |
| 835.91 | 3.84 | 3.84 |
| 765.82 | 4.02 | 4.02 |
| 865.89 | 2.91 | 2.91 |
| 954.92 | 3.57 | 3.57 |
| 879.92 | 3.22 | 3.22 |
| 761.78 | 2.74 | 2.74 |
| 653.67 | 4.25 | 4.25 |
| 760.83 | 4.76 | 4.76 |
| 638.66 | 3.43 | 3.43 |
| 780.78 | 3.39 | 3.39 |
| 816.82 | 4.23 | 4.23 |
| 796.78 | 3.09 | 3.09 |
| 839.94 | 4.61 | 4.61 |
| 865.81 | 3.91 | 3.91 |
| 810.77 | 2.77 | 2.77 |
| 760.83 | 4.76 | 4.76 |
| 760.79 | 3.20 | 3.20 |
| 657.66 | 4.16 | 4.16 |