Basic Information
ID: ALA4418818
Type: ADME
Description: Drug metabolism in heparinized pooled human plasma at pH 7.5 assessed as formation of (S)-2-(2-ethoxy-4-(5-((((R)-2-((R)-1-(N-hydroxyformamido)propyl)heptanamido)methyl) carbamoyl)furan-2-yl)benzamido)succinic acid at 100 to 2000 ng/ml incubated up to 4 or 24 hrs by by LC-MS/MS analysis
Organism: Homo sapiens
Tissue: Plasma
Activity Charts
Bioactivity
Activity Types for Assay ALA4418818
Drug metabolism
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 716.79 | 3.74 | 3.74 |
| 828.87 | 3.78 | 3.78 |
| 766.80 | 4.02 | 4.02 |
| 803.83 | 3.59 | 3.59 |
| 779.84 | 4.08 | 4.08 |
| 730.81 | 4.13 | 4.13 |
| 850.80 | 4.92 | 4.92 |
| 768.79 | 4.46 | 4.46 |
| 765.82 | 4.05 | 4.05 |
| 808.88 | 5.14 | 5.14 |
| 744.75 | 3.14 | 3.14 |
| 750.80 | 4.32 | 4.32 |
| 765.82 | 4.05 | 4.05 |
| 751.79 | 3.59 | 3.59 |
| 849.93 | 4.15 | 4.15 |
| 732.78 | 3.24 | 3.24 |
| 781.77 | 3.92 | 3.92 |
| 731.80 | 3.68 | 3.68 |
| 793.87 | 4.82 | 4.82 |
| 752.77 | 3.72 | 3.72 |
| 804.77 | 5.03 | 5.03 |
| 796.83 | 4.03 | 4.03 |
| 778.86 | 5.14 | 5.14 |
| 750.80 | 3.94 | 3.94 |
| 736.78 | 4.01 | 4.01 |
| 814.89 | 4.33 | 4.33 |
| 853.93 | 4.14 | 4.14 |
| 795.80 | 4.23 | 4.23 |
| 846.78 | 3.79 | 3.79 |
| 802.84 | 4.20 | 4.20 |
| 784.79 | 4.16 | 4.16 |
| 765.82 | 3.47 | 3.47 |
| 801.85 | 4.80 | 4.80 |
| 840.88 | 3.40 | 3.40 |
| 717.77 | 3.29 | 3.29 |
| 796.83 | 4.03 | 4.03 |
| 857.83 | 2.70 | 2.70 |
| 841.92 | 3.84 | 3.84 |
| 834.80 | 5.04 | 5.04 |
| 757.73 | 2.35 | 2.35 |
| 796.85 | 5.27 | 5.27 |
| 857.93 | 4.75 | 4.75 |
| 845.70 | 4.78 | 4.78 |
| 802.84 | 4.20 | 4.20 |
| 708.77 | 4.15 | 4.15 |
| 746.81 | 3.72 | 3.72 |
| 732.78 | 4.11 | 4.11 |
| 843.91 | 3.41 | 3.41 |
| 835.91 | 3.84 | 3.84 |
| 751.79 | 3.59 | 3.59 |
| 765.82 | 4.02 | 4.02 |
| 835.91 | 4.80 | 4.80 |
| 818.80 | 5.34 | 5.34 |
| 751.79 | 4.40 | 4.40 |
| 801.25 | 4.67 | 4.67 |
| 832.90 | 3.86 | 3.86 |
| 839.94 | 4.61 | 4.61 |
| 768.79 | 4.46 | 4.46 |