Basic Information
ID: ALA4418819
Type: ADME
Description: Drug metabolism in heparinized pooled human plasma at pH 7.5 assessed as formation of (S)-2-(2-(carboxymethoxy)-4-(5-((((R)-2-((R)-1-(N-hydroxyformamido)propyl)heptanamido)methyl)carbamoyl)furan-2-yl)benzamido)succinic acid at 100 to 2000 ng/ml incubated up to 4 or 24 hrs by by LC-MS/MS analysis
Format: BAO_0000366
Organism: Homo sapiens
Tissue: Plasma
Target: ADMET(ALA612558)
Document: ALA4418493
Drug metabolism in heparinized pooled human plasma at pH 7.5 assessed as formation of (S)-2-(2-(carboxymethoxy)-4-(5-((((R)-2-((R)-1-(N-hydroxyformamido)propyl)heptanamido)methyl)carbamoyl)furan-2-yl)benzamido)succinic acid at 100 to 2000 ng/ml incubated up to 4 or 24 hrs by by LC-MS/MS analysis: 38
Activity Charts
Bioactivity
Activity Types for Assay ALA4418819
Drug metabolism
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 861.90 | 3.39 | 3.39 |
| 798.77 | 3.52 | 3.52 |
| 782.76 | 2.78 | 2.78 |
| 819.82 | 3.22 | 3.22 |
| 856.88 | 4.60 | 4.60 |
| 744.75 | 2.56 | 2.56 |
| 762.77 | 3.17 | 3.17 |
| 795.80 | 3.09 | 3.09 |
| 788.85 | 3.98 | 3.98 |
| 824.79 | 3.00 | 3.00 |
| 838.86 | 4.21 | 4.21 |
| 766.76 | 3.08 | 3.08 |
| 816.82 | 4.23 | 4.23 |
| 826.81 | 3.09 | 3.09 |
| 767.75 | 2.47 | 2.47 |
| 832.86 | 2.78 | 2.78 |
| 781.77 | 3.47 | 3.47 |
| 719.70 | 1.58 | 1.58 |
| 877.90 | 3.09 | 3.09 |
| 808.84 | 4.20 | 4.20 |
| 747.76 | 2.35 | 2.35 |
| 810.81 | 3.39 | 3.39 |
| 781.77 | 2.66 | 2.66 |
| 823.85 | 3.88 | 3.88 |
| 826.83 | 4.34 | 4.34 |
| 795.80 | 3.12 | 3.12 |
| 772.65 | 1.30 | 1.30 |
| 744.75 | 2.42 | 2.42 |
| 853.84 | 3.14 | 3.14 |
| 865.89 | 2.91 | 2.91 |
| 954.92 | 3.57 | 3.57 |
| 879.92 | 3.22 | 3.22 |
| 761.78 | 2.74 | 2.74 |
| 780.78 | 3.39 | 3.39 |
| 816.82 | 4.23 | 4.23 |
| 785.76 | 2.68 | 2.68 |
| 796.78 | 3.09 | 3.09 |
| 810.77 | 2.77 | 2.77 |
| 760.79 | 3.20 | 3.20 |