ID: ALA4418819
Type: ADME
Description: Drug metabolism in heparinized pooled human plasma at pH 7.5 assessed as formation of (S)-2-(2-(carboxymethoxy)-4-(5-((((R)-2-((R)-1-(N-hydroxyformamido)propyl)heptanamido)methyl)carbamoyl)furan-2-yl)benzamido)succinic acid at 100 to 2000 ng/ml incubated up to 4 or 24 hrs by by LC-MS/MS analysis
Organism: Homo sapiens
Tissue: Plasma
Bioactivity
Activity Types for Assay ALA4418819
Drug metabolism
Parent Molecular Weight | ALogP | Polar Surface Area |
---|---|---|
861.90 | 3.39 | 3.39 |
798.77 | 3.52 | 3.52 |
782.76 | 2.78 | 2.78 |
819.82 | 3.22 | 3.22 |
856.88 | 4.60 | 4.60 |
744.75 | 2.56 | 2.56 |
762.77 | 3.17 | 3.17 |
795.80 | 3.09 | 3.09 |
788.85 | 3.98 | 3.98 |
824.79 | 3.00 | 3.00 |
838.86 | 4.21 | 4.21 |
766.76 | 3.08 | 3.08 |
816.82 | 4.23 | 4.23 |
826.81 | 3.09 | 3.09 |
767.75 | 2.47 | 2.47 |
832.86 | 2.78 | 2.78 |
781.77 | 3.47 | 3.47 |
719.70 | 1.58 | 1.58 |
877.90 | 3.09 | 3.09 |
808.84 | 4.20 | 4.20 |
747.76 | 2.35 | 2.35 |
810.81 | 3.39 | 3.39 |
781.77 | 2.66 | 2.66 |
823.85 | 3.88 | 3.88 |
826.83 | 4.34 | 4.34 |
795.80 | 3.12 | 3.12 |
772.65 | 1.30 | 1.30 |
744.75 | 2.42 | 2.42 |
853.84 | 3.14 | 3.14 |
865.89 | 2.91 | 2.91 |
954.92 | 3.57 | 3.57 |
879.92 | 3.22 | 3.22 |
761.78 | 2.74 | 2.74 |
780.78 | 3.39 | 3.39 |
816.82 | 4.23 | 4.23 |
785.76 | 2.68 | 2.68 |
796.78 | 3.09 | 3.09 |
810.77 | 2.77 | 2.77 |
760.79 | 3.20 | 3.20 |