Basic Information
ID: ALA4418837
Type: Binding
Description: Inhibition of recombinant Escherichia coli UMP kinase pyrH catalyzed UMP phosphorylation in presence of GTP and ATP incubated for 1 hr by luminescence based assay
Organism: Escherichia coli
Activity Charts
Bioactivity
Activity Types for Assay ALA4418837
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 407.64 | 3.54 | 3.54 |
| 226.23 | 2.23 | 2.23 |
| 258.28 | 3.93 | 3.93 |
| 367.21 | 3.17 | 3.17 |
| 490.48 | 5.85 | 5.85 |
| 323.48 | 2.77 | 2.77 |
| 466.57 | 5.13 | 5.13 |
| 265.25 | 1.88 | 1.88 |
| 482.29 | 4.38 | 4.38 |
| 511.82 | 8.05 | 8.05 |
| 260.21 | 2.34 | 2.34 |
| 357.45 | 2.72 | 2.72 |
| 452.47 | 4.96 | 4.96 |
| 358.44 | 3.03 | 3.03 |
| 471.56 | 2.84 | 2.84 |
| 374.51 | 4.54 | 4.54 |
| 385.42 | 4.60 | 4.60 |
| 412.47 | 5.96 | 5.96 |
| 361.47 | 5.22 | 5.22 |
| 398.51 | 5.38 | 5.38 |
| 492.52 | 3.71 | 3.71 |
| 377.22 | 2.62 | 2.62 |
| 453.32 | 4.79 | 4.79 |
| 567.71 | 8.21 | 8.21 |
| 508.49 | 3.68 | 3.68 |
| 416.22 | 3.01 | 3.01 |
| 563.70 | 7.40 | 7.40 |
| 327.43 | 4.24 | 4.24 |
| 392.41 | 3.92 | 3.92 |
| 475.53 | 3.70 | 3.70 |
| 441.61 | 5.43 | 5.43 |
| 443.32 | 5.32 | 5.32 |
| 446.35 | 5.70 | 5.70 |
| 426.40 | 4.73 | 4.73 |
| 424.36 | 2.39 | 2.39 |
| 546.52 | 4.82 | 4.82 |
| 453.91 | 3.30 | 3.30 |
| 425.87 | 4.10 | 4.10 |
| 390.47 | 4.17 | 4.17 |
| 391.81 | 3.80 | 3.80 |
| 442.86 | 4.89 | 4.89 |
| 391.25 | 2.93 | 2.93 |
| 438.50 | 5.59 | 5.59 |
| 425.78 | 4.69 | 4.69 |
| 367.21 | 3.17 | 3.17 |
| 335.36 | 4.50 | 4.50 |
| 368.41 | 2.75 | 2.75 |
| 534.06 | 6.33 | 6.33 |
| 396.45 | 3.18 | 3.18 |
| 421.33 | 1.02 | 1.02 |
| 588.55 | 5.25 | 5.25 |
| 411.53 | 3.33 | 3.33 |
| 322.36 | 4.43 | 4.43 |
| 410.23 | 3.60 | 3.60 |
| 429.89 | 4.62 | 4.62 |
| 461.49 | 6.50 | 6.50 |
| 466.48 | 3.62 | 3.62 |
| 420.52 | 6.11 | 6.11 |
| 558.68 | 5.83 | 5.83 |
| 257.32 | 1.98 | 1.98 |
| 472.59 | 4.09 | 4.09 |
| 229.19 | 2.55 | 2.55 |
| 350.37 | 4.21 | 4.21 |
| 300.32 | 3.47 | 3.47 |
| 495.35 | 4.74 | 4.74 |
| 431.52 | 3.93 | 3.93 |
| 480.93 | 4.49 | 4.49 |
| 453.86 | 4.34 | 4.34 |
| 401.26 | 5.19 | 5.19 |
| 471.31 | 4.68 | 4.68 |
| 442.50 | 5.97 | 5.97 |
| 289.38 | 4.42 | 4.42 |
| 494.31 | 5.54 | 5.54 |
| 470.32 | 4.21 | 4.21 |
| 578.27 | 7.12 | 7.12 |
| 419.78 | 3.07 | 3.07 |
| 485.93 | 5.42 | 5.42 |
| 434.40 | 3.38 | 3.38 |
| 398.46 | 4.97 | 4.97 |
| 454.47 | 2.73 | 2.73 |
| 352.65 | 2.84 | 2.84 |
| 545.59 | 7.71 | 7.71 |
| 293.32 | 3.53 | 3.53 |
| 482.36 | 4.08 | 4.08 |
| 564.69 | 6.79 | 6.79 |
| 305.74 | 4.17 | 4.17 |
| 452.88 | 4.13 | 4.13 |
| 492.54 | 3.62 | 3.62 |
| 452.51 | 2.20 | 2.20 |
| 487.59 | 5.00 | 5.00 |
| 369.21 | 5.60 | 5.60 |
| 385.22 | 3.08 | 3.08 |
| 374.40 | 3.41 | 3.41 |
| 383.92 | 4.59 | 4.59 |
| 595.05 | 6.19 | 6.19 |
| 385.47 | 4.76 | 4.76 |
| 500.44 | 6.07 | 6.07 |
| 401.90 | 5.59 | 5.59 |
| 572.24 | 2.80 | 2.80 |
| 392.80 | 3.19 | 3.19 |
| 451.75 | 4.83 | 4.83 |
| 558.26 | 7.62 | 7.62 |
| 527.40 | 3.11 | 3.11 |
| 453.86 | 4.34 | 4.34 |
| 514.83 | 5.34 | 5.34 |
| 431.34 | 4.39 | 4.39 |
| 280.35 | 3.62 | 3.62 |
| 369.40 | 2.82 | 2.82 |
| 427.32 | 5.56 | 5.56 |
| 386.41 | 2.91 | 2.91 |
| 432.26 | 5.33 | 5.33 |
| 418.23 | 4.69 | 4.69 |
| 557.48 | 4.76 | 4.76 |
| 411.59 | 5.42 | 5.42 |
| 263.32 | 0.67 | 0.67 |
| 482.36 | 4.08 | 4.08 |
| 381.24 | 4.57 | 4.57 |
| 458.66 | 3.37 | 3.37 |
| 484.25 | 3.14 | 3.14 |
| 581.64 | 7.26 | 7.26 |
| 412.57 | 4.65 | 4.65 |
| 444.35 | 4.34 | 4.34 |
| 459.50 | 6.01 | 6.01 |
| 441.78 | 3.76 | 3.76 |
| 407.88 | 3.96 | 3.96 |
| 388.43 | 3.71 | 3.71 |
| 464.34 | 3.87 | 3.87 |
| 426.50 | 5.64 | 5.64 |
| 435.45 | 5.96 | 5.96 |
| 375.18 | 2.77 | 2.77 |
| 395.40 | 1.48 | 1.48 |
| 392.85 | 4.36 | 4.36 |
| 279.34 | 2.13 | 2.13 |
| 418.52 | 5.72 | 5.72 |
| 374.43 | 2.45 | 2.45 |
| 495.61 | 4.31 | 4.31 |
| 451.41 | 6.29 | 6.29 |
| 573.70 | 6.26 | 6.26 |
| 557.21 | 4.21 | 4.21 |
| 408.15 | 2.30 | 2.30 |
| 353.43 | 3.37 | 3.37 |
| 425.23 | 4.89 | 4.89 |
| 451.33 | 5.10 | 5.10 |
| 318.79 | 4.50 | 4.50 |
| 454.36 | 4.80 | 4.80 |
| 338.36 | 3.73 | 3.73 |
| 438.89 | 5.69 | 5.69 |
| 390.47 | 4.94 | 4.94 |
| 414.47 | 5.13 | 5.13 |
| 376.35 | 2.43 | 2.43 |
| 525.92 | 4.08 | 4.08 |
| 449.56 | 5.91 | 5.91 |
| 415.45 | 5.40 | 5.40 |
| 447.93 | 5.13 | 5.13 |
| 514.38 | 4.61 | 4.61 |
| 498.36 | 3.41 | 3.41 |
| 482.36 | 4.08 | 4.08 |
| 275.33 | 0.84 | 0.84 |