Basic Information
ID: ALA4418840
Type: Binding
Description: Inhibition of GST-tagged CUL4A/Rbxl ubiquitin ligase activity (unknown origin) assessed as reduction in reconstituted DDB1 ubiquitination in presence of ubiquitin, El, E2 and DDB1 incubated for 1 hr by Western blotting analysis
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4418840
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 398.03 | 3.83 | 3.83 |
| 282.37 | 2.37 | 2.37 |
| 322.32 | 2.92 | 2.92 |
| 267.36 | 3.18 | 3.18 |
| 297.38 | 3.54 | 3.54 |
| 256.33 | 3.38 | 3.38 |
| 282.37 | 3.41 | 3.41 |
| 383.02 | 3.10 | 3.10 |
| 272.31 | 2.04 | 2.04 |
| 351.20 | 2.81 | 2.81 |
| 240.05 | 1.98 | 1.98 |
| 260.65 | 2.65 | 2.65 |
| 284.36 | 4.30 | 4.30 |
| 299.32 | 1.81 | 1.81 |
| 254.32 | 1.90 | 1.90 |
| 288.20 | 3.99 | 3.99 |
| 260.35 | 1.97 | 1.97 |
| 372.88 | 3.77 | 3.77 |
| 322.31 | 2.92 | 2.92 |
| 274.68 | 3.04 | 3.04 |
| 286.19 | 3.74 | 3.74 |
| 305.11 | 2.76 | 2.76 |
| 266.06 | 1.63 | 1.63 |
| 307.38 | 1.86 | 1.86 |
| 242.30 | 3.75 | 3.75 |
| 282.09 | 1.57 | 1.57 |
| 319.13 | 3.15 | 3.15 |
| 255.31 | 1.30 | 1.30 |
| 282.37 | 3.87 | 3.87 |
| 290.30 | 2.18 | 2.18 |
| 246.29 | 1.51 | 1.51 |
| 272.69 | 1.39 | 1.39 |
| 244.28 | 1.50 | 1.50 |
| 309.13 | 3.70 | 3.70 |
| 304.42 | 1.88 | 1.88 |
| 312.35 | 1.83 | 1.83 |
| 296.40 | 4.17 | 4.17 |