Assay Report Card

Basic Information

ID: ALA4418844

Type: Binding

Description: Inhibition of CUL1 in human U20S cells assessed as reduction in TNF-alpha-induced IkappaB-alpha degradation at 50 uM incubated for 2 hrs followed by TNFalpha stimulation for 15 mins by Western blotting analysis

Organism: Homo sapiens

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
256.333.383.38
282.373.413.41
260.351.971.97
272.312.042.04
244.281.501.50
296.404.174.17