Basic Information
ID: ALA4418863
Type: Binding
Description: Inhibition of His6-tagged human neuraminidase-1 expressed in HEK293 cells pre-incubated for 15 mins before 4MU-NANA substrate addition and measured after 30 mins by fluorescence based assay
Organism: Homo sapiens
Cell type: HEK293
Activity Charts
Bioactivity
Activity Types for Assay ALA4418863
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 291.26 | -3.07 | -3.07 |
| 332.31 | -3.58 | -3.58 |
| 394.38 | -1.63 | -1.63 |
| 372.33 | -3.27 | -3.27 |
| 319.31 | -2.43 | -2.43 |
| 448.43 | -1.09 | -1.09 |
| 510.50 | 0.69 | 0.69 |
| 372.37 | -2.14 | -2.14 |
| 503.47 | -1.91 | -1.91 |
| 486.40 | -0.08 | -0.08 |
| 462.42 | -1.40 | -1.40 |
| 461.43 | -1.44 | -1.44 |
| 374.39 | -1.75 | -1.75 |
| 494.50 | 0.57 | 0.57 |
| 475.46 | -1.14 | -1.14 |
| 374.39 | -1.75 | -1.75 |
| 461.48 | -1.03 | -1.03 |
| 487.43 | -0.08 | -0.08 |
| 346.34 | -2.53 | -2.53 |
| 433.42 | -1.52 | -1.52 |
| 432.43 | -0.79 | -0.79 |
| 358.35 | -2.53 | -2.53 |
| 436.40 | -0.96 | -0.96 |
| 535.56 | 0.06 | 0.06 |
| 576.52 | -1.62 | -1.62 |
| 451.43 | -1.67 | -1.67 |
| 452.40 | -1.99 | -1.99 |
| 550.57 | -1.38 | -1.38 |
| 388.42 | -2.16 | -2.16 |
| 305.28 | -2.68 | -2.68 |
| 449.42 | -2.55 | -2.55 |
| 451.43 | -1.67 | -1.67 |
| 374.39 | -1.75 | -1.75 |
| 374.39 | -1.90 | -1.90 |
| 448.43 | -1.82 | -1.82 |
| 331.32 | -2.29 | -2.29 |
| 402.44 | -0.97 | -0.97 |
| 416.47 | -0.58 | -0.58 |
| 347.36 | -1.65 | -1.65 |
| 412.44 | -1.03 | -1.03 |
| 402.44 | -0.97 | -0.97 |
| 402.44 | -0.97 | -0.97 |
| 409.40 | -2.05 | -2.05 |
| 502.40 | -1.11 | -1.11 |
| 319.31 | -2.29 | -2.29 |
| 360.36 | -2.14 | -2.14 |
| 361.39 | -1.12 | -1.12 |
| 388.42 | -1.36 | -1.36 |
| 409.40 | -2.05 | -2.05 |
| 353.33 | -1.77 | -1.77 |
| 360.36 | -2.29 | -2.29 |
| 444.53 | 0.20 | 0.20 |
| 464.43 | -2.12 | -2.12 |
| 317.29 | -2.68 | -2.68 |
| 347.36 | -1.51 | -1.51 |
| 491.46 | -2.17 | -2.17 |
| 478.41 | -2.43 | -2.43 |
| 477.47 | -2.06 | -2.06 |
| 416.47 | -0.58 | -0.58 |
| 388.42 | -1.36 | -1.36 |
| 388.42 | -1.51 | -1.51 |
| 388.42 | -1.36 | -1.36 |
| 333.34 | -2.04 | -2.04 |
| 469.53 | 2.02 | 2.02 |
| 402.44 | -1.12 | -1.12 |
| 475.46 | -1.84 | -1.84 |
| 537.53 | 0.15 | 0.15 |
| 318.24 | -2.18 | -2.18 |
| 361.39 | -1.26 | -1.26 |
| 416.47 | -0.73 | -0.73 |
| 375.42 | -0.87 | -0.87 |